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Physiologically active substances

Assignee: Sankyo Co Ltd
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Filing: 1975-05-12
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Granted: 1976-09-28
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Expires: 1995-05-12
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Abstract

Abstract Physiologically active substances ML-236 of the formula ##SPC1## Wherein R is hydrogen atom, hydroxy group or 2-methylbutyryloxy group having cholesterol- and lipid-lowering effects in blood and liver and thus utility as hypocholesteremic and hypolipemic medicaments. They are obtained by cultivation of an ML-236-producing microorganism belonging to the genus Penicillium in a culture medium and subsequent recovery thereof from a cultured broth.

Inventors

  • 👤 Akira Endo
  • 👤 Masao Kuroda
  • 👤 Akira Terahara
  • 👤 Yoshio Tsujita
  • 👤 Chihiro Tamura

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 05:49
CPC Classifications
C; C12; C12P; C12P17/00; C12P17/02; C12P17/06; A; A61; A61P; A61P9/00; A61P9/10; C07; C07D; C07D309/00; C07D309/16; C07D309/28; C07D309/30; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/911; Y10S435/933

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 16 words
A compound having the formula ##SPC4## wherein R is hydrogen atom, hydroxy group or 2-methylbutyryloxy group.
Claim 2
Dependent Claim 16 words
A compound having the formula ##SPC4## wherein R is hydrogen atom, hydroxy group or 2-methylbutyryloxy group.
Claim 3
Dependent Claim 12 words
A compound according to claim 1 wherein said R is hydroxy group.
Claim 4
Dependent Claim 12 words
A compound according to claim 1 wherein said R is 2-methylbutyryloxy group.
Claim 5
Dependent Claim 12 words
A compound according to claim 1 wherein said R is hydrogen atom.

References Cited (Backward Citations)

US3842092A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-09-28 1980-03-29 1980-09-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-09-28 1984-03-29 1984-09-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-09-28 1988-03-29 1988-09-28 $7700.00 Window Closed / Lapsed

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