Patent US3981179A successfully refreshed from Google Patents.
US3981179A
Expired / Lapsed
US
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Fluid detecting system
Assignee: Applied Automation Inc
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Filing: 1975-10-15
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Granted: 1976-09-21
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Expires: 1995-10-15
Abstract
Abstract A system and method wherein a sample fluid in a reference carrier fluid stream is passed through a sample cell to a point of dilution and then through a reference cell, and a detector means indicates a characteristic of the sample fluid by simultaneously comparing at least one identical characteristic of the fluid in the sample cell and the fluid in the reference cell.
Inventors
- 👤 Lewis B. Roof
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:55
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/62
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
173 words
A fluid detecting system comprising a sample cell having an inlet and an outlet, a means capable of providing sample fluid and carrier fluid to the inlet of said sample cell, a dilution tank having an inlet and an outlet, a means capable of providing fluid communication between said sample cell outlet and said dilution tank inlet, a reference cell having an inlet and outlet, a means capable of providing fluid communication between said dilution tank outlet and said reference cell inlet, and a detector means adapted to compare at least one characteristic of the fluids in the sample cell with the same characteristic of the fluids in the reference cell, wherein said dilution tank is of such size that after said dilution tank has been filled with carrier fluid any sample fluid component coming from the sample cell will in said dilution tank become so diluted with carrier that the detector means comparison will not be significantly affected by the level of sample fluid component in the fluids in said reference cell.
Claim 2
Dependent Claim
173 words
A fluid detecting system comprising a sample cell having an inlet and an outlet, a means capable of providing sample fluid and carrier fluid to the inlet of said sample cell, a dilution tank having an inlet and an outlet, a means capable of providing fluid communication between said sample cell outlet and said dilution tank inlet, a reference cell having an inlet and outlet, a means capable of providing fluid communication between said dilution tank outlet and said reference cell inlet, and a detector means adapted to compare at least one characteristic of the fluids in the sample cell with the same characteristic of the fluids in the reference cell, wherein said dilution tank is of such size that after said dilution tank has been filled with carrier fluid any sample fluid component coming from the sample cell will in said dilution tank become so diluted with carrier that the detector means comparison will not be significantly affected by the level of sample fluid component in the fluids in said reference cell.
Claim 3
Dependent Claim
61 words
A fluid detecting system according to claim 1 wherein said outlet from said reference cell contains a restrictor means which restricts the flow out of the detecting system in such a manner as to maintain pressure in the cells to prevent the formation of bubbles in either the reference cell or the sample cell when the detecting system is in operation.
Claim 4
Dependent Claim
21 words
A fluid detecting system according to claim 2 wherein the source of sample and carrier fluid is a liquid chromatographic column.
Claim 5
Dependent Claim
37 words
A fluid detecting system according to claim 3 wherein the dilution tank is from about 1000 to about 100,000 times greater in volume than the volume of the sample to be separated in the liquid chromatographic column.
Claim 6
Dependent Claim
61 words
A fluid detecting system according to claim 4 wherein said restrictor in said reference cell outlet is capable of maintaining the pressure in said sample cell and said reference cell at a substantially identical level in the range of 5 to 50 psi when the pressure upstream of the liquid chromatographic column is in the range of 1000 to 5000 psi.
Claim 7
Dependent Claim
115 words
A fluid detecting system according to claim 5 wherein the liquid chromatographic column is 0.1 to 4 meters in length, 2 to 5 millimeters in internal diameter, and packed with spherical or irregular beads 5 to 75 micrometers in diameter, and the sample fluid is provided for the column by way of a sample valve adapted to trap a 2 to 15 microliter sample and to use the flow of carrier fluid to carry said sample into said column, the tubings and fittings in the flow path between said sample valve and said column and between said column and said sample cell having such small volume that peak spreading in that flow path is minimal.
Claim 8
Dependent Claim
20 words
A fluid detecting system according to claim 6 wherein the dilution tank has a volume of about 150 cubic centimeters.
Claim 9
Dependent Claim
35 words
A fluid detecting system according to claim 3 wherein the dilution tank has a volume of from about 10,000 to about 75,000 times the volume of sample to be separated in the liquid chromatographic column.
Claim 10
Dependent Claim
160 words
A process for the analysis of a fluid stream which is predominately a carrier fluid containing at least one other fluid component in amounts that can be detected by the detector employed in the analysis comprising filling a first detection zone and a second detection zone with said aforementioned carrier fluid containing no amounts of other substances which can be detected by the detector being employed, then passing the fluid to be analyzed through said first detection zone, passing the fluid from said first detection zone to a dilution zone, passing the thus diluted fluid from the dilution zone through said second detection zone, the fluid being diluted with said carrier fluid in said dilution zone until only said carrier fluid is detectable in said second detector zone by the detector being employed, and comparing at least one characteristic of the fluids in the two detection zones as the fluid to be analyzed is passed through said first detection zone.
Claim 11
Dependent Claim
160 words
A process for the analysis of a fluid stream which is predominately a carrier fluid containing at least one other fluid component in amounts that can be detected by the detector employed in the analysis comprising filling a first detection zone and a second detection zone with said aforementioned carrier fluid containing no amounts of other substances which can be detected by the detector being employed, then passing the fluid to be analyzed through said first detection zone, passing the fluid from said first detection zone to a dilution zone, passing the thus diluted fluid from the dilution zone through said second detection zone, the fluid being diluted with said carrier fluid in said dilution zone until only said carrier fluid is detectable in said second detector zone by the detector being employed, and comparing at least one characteristic of the fluids in the two detection zones as the fluid to be analyzed is passed through said first detection zone.
Claim 12
Dependent Claim
113 words
A process according to claim 9 wherein the dilution of the fluid coming from said first detection zone is accomplished by passing said fluid from said first detection zone into a dilution zone containing an amount of said carrier fluid such that if the noncarrier component, that is the total fluid component in the amount of said fluid stream analyzed other than the carrier fluid component, were combined with the amount of carrier fluid in the dilution zone, said noncarrier component of said fluid stream would be so diluted that the detector employed would not be significantly affected by the presence of noncarrier component in the fluid passing into the second detection zone.
Claim 13
Dependent Claim
39 words
A process according to claim 10 wherein the amount of carrier fluid in dilution zone is from 1000 to 100,000 times the volume of noncarrier component contained in the amount of the fluid stream that is subjected to analysis.
Claim 14
Dependent Claim
20 words
A process according to claim 11 wherein the fluid stream that is analyzed is the eluent from a chromatographic column.
Claim 15
Dependent Claim
22 words
A process according to claim 12 wherein the fluid stream that is analyzed is a liquid eluent from a liquid chromatographic column.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-21 | 1980-03-22 | 1980-09-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-21 | 1984-03-22 | 1984-09-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-21 | 1988-03-22 | 1988-09-21 | $7700.00 | Window Closed / Lapsed |