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US3980642A
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15-Substitute D-ω-pentanorprostaglandins
Assignee: Pfizer Inc
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Filing: 1975-11-19
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Granted: 1976-09-14
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Expires: 1995-11-19
Abstract
Abstract The 15-substituted- omega -pentanorprostaglandins and various intermediates employed in their preparation. The novel prostaglandins of this invention have been found to have activity profiles comparable to the parent prostaglandins, but exhibit a greater tissue specificity of action.
Inventors
- 👤 Hans-Jurgen E. Hess
- 👤 Michael R. Johnson
- 👤 Jasjit S. Bindra
- 👤 Thomas K. Schaaf
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 08:19
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/547; C07F9/6553; C07F9/655345; C07C; C07C405/00; B; B63; B63B; B63B2211/00; B63B2211/02
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
65 words
A compound of the structure: ##SPC13## wherein Ar is α- or β-furyl; α- or β-thienyl; R is hydrogen or lower alkyl; Thp is 2-tetrahydropyranyl; n is an integer from 0 to 5; with the proviso that when n is zero, Z is a single bond; W is a single bond or a cis double bond; and Z is a single bond or trans double bond.
Claim 2
Dependent Claim
65 words
A compound of the structure: ##SPC13## wherein Ar is α- or β-furyl; α- or β-thienyl; R is hydrogen or lower alkyl; Thp is 2-tetrahydropyranyl; n is an integer from 0 to 5; with the proviso that when n is zero, Z is a single bond; W is a single bond or a cis double bond; and Z is a single bond or trans double bond.
Claim 3
Dependent Claim
65 words
A compound of the structure: ##SPC14## wherein Ar is α- or β-furyl; α- or β-thienyl; R is hydrogen or lower alkyl; Thp is 2-tetrahydropyranyl; n is an integer from 0 to 5; with the proviso that when n is zero, Z is a single bond; W is a single bond or a cis double bond; and Z is a single bond or trans double bond.
Claim 4
Dependent Claim
65 words
A compound of the structure: ##SPC14## wherein Ar is α- or β-furyl; α- or β-thienyl; R is hydrogen or lower alkyl; Thp is 2-tetrahydropyranyl; n is an integer from 0 to 5; with the proviso that when n is zero, Z is a single bond; W is a single bond or a cis double bond; and Z is a single bond or trans double bond.
Claim 5
Dependent Claim
28 words
A compound of the formula: ##SPC15## wherein Ar is α- or β-furyl; or α- or β-thienyl; n is an integer from 1 to 5; and THP is 2-tetrahydropyranyl.
Claim 6
Dependent Claim
28 words
A compound of the formula: ##SPC15## wherein Ar is α- or β-furyl; or α- or β-thienyl; n is an integer from 1 to 5; and THP is 2-tetrahydropyranyl.
Claim 7
Dependent Claim
28 words
A compound of the formula: ##SPC16## wherein Ar is α- or β-furyl or α- or β-thienyl; n is an integer from 1 to 5; and THP is 2-tetrahydropyranyl.
Claim 8
Dependent Claim
28 words
A compound of the formula: ##SPC16## wherein Ar is α- or β-furyl or α- or β-thienyl; n is an integer from 1 to 5; and THP is 2-tetrahydropyranyl.
Claim 9
Dependent Claim
28 words
A compound of the formula: ##SPC17## wherein Ar is α- or β-furyl or α- or β-thienyl; n is an integer from 1 to 5; and THP is 2-tetrahydropyranyl.
Claim 10
Dependent Claim
28 words
A compound of the formula: ##SPC17## wherein Ar is α- or β-furyl or α- or β-thienyl; n is an integer from 1 to 5; and THP is 2-tetrahydropyranyl.
References Cited (Backward Citations)
US3928391A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-14 | 1980-03-15 | 1980-09-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-14 | 1984-03-15 | 1984-09-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-14 | 1988-03-15 | 1988-09-14 | $7700.00 | Window Closed / Lapsed |