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US3976779A
Expired / Lapsed
US
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1,2,3,4-Tetrahydro-carbazole compounds and β-adrenergic compositions
Assignee: Roche Diagnostics GmbH
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Filing: 1975-04-16
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Granted: 1976-08-24
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Expires: 1995-04-16
Abstract
Abstract New 1,2,3,4-tetra-hydrocarbazole derivatives of the formula:
Inventors
- 👤 Herbert Leinert
- 👤 Alfred Popelak
- 👤 Kurt Stach
- 👤 Wolfgang Bartsch
- 👤 Karl Dietmann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 17:07
CPC Classifications
C; C07; C07D; C07D209/00; C07D209/56; C07D209/80; C07D209/82; C07D209/88
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
26 words
1,2,3,4-Tetrahydro-carbazole compound of the formula: ##SPC5## wherein R 1 is straight-chained or branched alkyl of up to 8 carbon atoms, or a pharmacologically compatible salt thereof.
Claim 2
Dependent Claim
26 words
1,2,3,4-Tetrahydro-carbazole compound of the formula: ##SPC5## wherein R 1 is straight-chained or branched alkyl of up to 8 carbon atoms, or a pharmacologically compatible salt thereof.
Claim 3
Dependent Claim
16 words
1,2,3,4-Tetrahydro-carbazole compound as claimed in claim 1 wherein R 1 contains up to 5 carbon atoms.
Claim 4
Dependent Claim
16 words
1,2,3,4-Tetrahydro-carbazole compound as claimed in claim 1 wherein R 1 contains 3 to 5 carbon atoms.
Claim 5
Dependent Claim
12 words
1,2,3,4-Tetrahydro-carbazole compound as claimed in claim 1 wherein R 1 is branched.
Claim 6
Dependent Claim
20 words
1,2,3,4-Tetrahydro-carbazole compound as claimed in claim 1 wherein R 1 is branched and contains from 3 to 5 carbon atoms.
Claim 7
Dependent Claim
10 words
1,2,3,4-Tetrahydro-carbazole compound as claimed in claim 1 designated 1,2,3,4-Tetrahydro-5-(2-hydroxyl-3-tert. butylamino-propoxy)-carbazole.
Claim 8
Dependent Claim
9 words
1,2,3,4-Tetrahydro-carbazole compound as claimed in claim 1 designated 1,2,3,4-tetrahydro-5-(2-hydroxyl-3-isopropylamino-propoxy)-carbazole.
Claim 9
Dependent Claim
22 words
Composition comprising a β-adrenergically effective amount of a 1,2,3,4-tetrahydro-carbazole compound as claimed in claim 1 in admixture with a pharmaceutically acceptable carrier.
Claim 10
Dependent Claim
47 words
Method of combating cardiac or circulatory insufficiency susceptible to treatment by β-adrenergic agents which method comprises administering to the subject a 1,2,3,4-Tetrahydro-carbazole compound of the formula: ##SPC6## wherein R 1 is straight-chained or branched alkyl of up to 8 carbon atoms or a pharmacologically compatible salt thereof.
Claim 11
Dependent Claim
47 words
Method of combating cardiac or circulatory insufficiency susceptible to treatment by β-adrenergic agents which method comprises administering to the subject a 1,2,3,4-Tetrahydro-carbazole compound of the formula: ##SPC6## wherein R 1 is straight-chained or branched alkyl of up to 8 carbon atoms or a pharmacologically compatible salt thereof.
Claim 12
Dependent Claim
22 words
Method as claimed in claim 9 wherein R 1 in the formula is branched alkyl of from 3 to 5 carbon atoms.
Claim 13
Dependent Claim
12 words
Method claimed in claim 9 wherein the said insufficiency is cardiac hypoxia.
Claim 14
Dependent Claim
20 words
Method as claimed in claim 9 wherein said compound is administered in a dosage of from 1 to 40 mg.
Claim 15
Dependent Claim
19 words
Method as claimed in claim 9 wherein said compound is at least one of the following: 1,2,3,4-tetrahydro-5-(2-hydroxy-3-isopropylamino-propoxy)-carbazole and 1,2,3,4-tetrahydro-5-(2-hydroxy-3-tert.butylamino-propoxy)-carbazole.
References Cited (Backward Citations)
US2731474A
Cited
US3663607A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-08-24 | 1980-02-23 | 1980-08-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-08-24 | 1984-02-23 | 1984-08-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-08-24 | 1988-02-23 | 1988-08-24 | $7700.00 | Window Closed / Lapsed |