US3976667A
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Steffimycinone, 7-deoxysteffimycinone and derivatives
Assignee: Pharmacia and Upjohn Co
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Filing: 1975-06-19
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Granted: 1976-08-24
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Expires: 1995-06-19
Abstract
Abstract Antibiotic steffimycinone (U-25,055), produced by acid hydrolysis or methanolysis of antibiotic steffimycin (U-20,661), or steffimycin B, and 7-deoxysteffimycinone (U-25,920) produced by hydrogenolysis of steffimycin or steffimycin B (U-40,615). Steffimycinone is active against various microorganisms, for example, Bacillus subtilis, Mycobacterium avium and Bacillus cereus; 7-deoxysteffimycinone is active against Sarcina lutea and Mycobacterium avium. Thus, these antibiotics can be used to inhibit the growth of the above microorganisms in various environments.
Inventors
- 👤 Robert C. Kelly
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 21:17
CPC Classifications
C; C07; C07C; C07C50/00; C07C50/26; C07C50/36
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
17 words
Steffimycinone, a compound having the following structure: ##SPC4## and non-toxic alkali and alkaline earth metal salts thereof.
Claim 2
Dependent Claim
17 words
Steffimycinone, a compound having the following structure: ##SPC4## and non-toxic alkali and alkaline earth metal salts thereof.
Claim 3
Dependent Claim
17 words
7-Deoxysteffimycinone, a compound having the following structure: ##SPC5## and non-toxic alkali and alkaline earth metal salts thereof.
Claim 4
Dependent Claim
17 words
7-Deoxysteffimycinone, a compound having the following structure: ##SPC5## and non-toxic alkali and alkaline earth metal salts thereof.
Claim 5
Dependent Claim
42 words
4,6,7-Tri-O-acylates of steffimycinone wherein said acyl group consists of hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive; halo-, nitro-, hydroxy-, amino-, cyano-, thiocyano-, and lower alkoxy-substituted hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive.
Claim 6
Dependent Claim
42 words
4,6,7-Tri-O-acylates of steffimycinone wherein said acyl group consists of hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive; halo-, nitro-, hydroxy-, amino-, cyano-, thiocyano-, and lower alkoxy-substituted hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive.
Claim 7
Dependent Claim
42 words
4,6-Di-O-acylates of 7-deoxysteffimycinone wherein said acyl group consists of hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive; halo-, nitro-, hydroxy-, amino-, cyano-, thiocyano-, and lower alkoxy-substituted hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive.
Claim 8
Dependent Claim
42 words
4,6-Di-O-acylates of 7-deoxysteffimycinone wherein said acyl group consists of hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive; halo-, nitro-, hydroxy-, amino-, cyano-, thiocyano-, and lower alkoxy-substituted hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-08-24 | 1980-02-23 | 1980-08-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-08-24 | 1984-02-23 | 1984-08-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-08-24 | 1988-02-23 | 1988-08-24 | $7700.00 | Window Closed / Lapsed |