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US3969508A Expired / Lapsed US ⏱️ 0.0 years remaining

Lowering the concentration of plasma triglycerides

Assignee: GlaxoSmithKline LLC
•
Filing: 1974-11-27
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Granted: 1976-07-13
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Expires: 1994-11-27
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Abstract

Abstract Hypolipidemic compositions containing 4-(2-thenoyl)-2,3-dichlorophenoxyacetic acid, its alkali metal salts or pharmaceutically acceptable base addition salts and methods of producing hypolipidemic activity by administering said compound. Combinations with other useful agents are also disclosed.

Inventors

  • 👤 Nicholas W. DiTullio
  • 👤 Charles P. Lowman
  • 👤 Alfred R. Maass
  • 👤 Harry L. Saunders

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 11:03
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/38; A61K31/395; A61K31/40; A61K31/435; A61K31/47; A61K31/475; A61K31/495; A61K31/505; A61K31/519; A61K31/525

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 54 words
A method of lowering the concentration of plasma triglycerides in a hyperlipidemic subject, which comprises administering internally to said subject a nontoxic amount, sufficient to lower said triglyceride concentration, of the compound 4-(2-thenoyl)-2,3-dichlorophenoxyacetic acid, an alkali metals salt of said acid or a pharmaceutically acceptable addition salt of said acid formed with a base.
Claim 2
Independent Claim 54 words
A method of lowering the concentration of plasma triglycerides in a hyperlipidemic subject, which comprises administering internally to said subject a nontoxic amount, sufficient to lower said triglyceride concentration, of the compound 4-(2-thenoyl)-2,3-dichlorophenoxyacetic acid, an alkali metals salt of said acid or a pharmaceutically acceptable addition salt of said acid formed with a base.
Claim 3
Dependent Claim 24 words
The method of claim 1 in which a daily dosage of from about 200 mg. to about 2000 mg. of active ingredient is administered.
Claim 4
Dependent Claim 29 words
The method of claim 1 in which dosage units containing from about 100 mg. to about 500 mg. of active ingredient are administered from 2 to 4 times daily.
Claim 5
Dependent Claim 20 words
The method of claim 1 in which the active ingredient is administered with a pharmaceutical carrier in dosage unit form.
Claim 6
Dependent Claim 11 words
The method of claim 4 in which the administration is orally.

References Cited (Backward Citations)

GB760114A Cited
US3402198A Cited
GB1228236A Cited
US3758506A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-07-13 1980-01-12 1980-07-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-07-13 1984-01-12 1984-07-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-07-13 1988-01-12 1988-07-13 $7700.00 Window Closed / Lapsed

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