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Method of preventing and treating thrombosis

Assignee: Otsuka Pharmaceutical Co Ltd
•
Filing: 1974-11-11
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Granted: 1976-07-13
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Expires: 1994-11-11
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Abstract

Abstract A method of preventing and treating thrombosis comprising administering a therapeutically effective amount of 5-(hydroxy-3-t-butylamino)propoxy-3,4-dihydrocarbostyril having the formula ##EQU1##

Inventors

  • 👤 Hideaki Kohri

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 15:03
CPC Classifications
C; C07; C07D; C07D215/00; C07D215/02; C07D215/16; C07D215/20; C07D215/22; C07D215/227

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 35 words
A method for preventing blood platelet aggregation and minimizing blood platelet adhesion comprising applying in vitro to blood or in vivo to mammals afflicted with thrombosis an effective amount of 5-(hydroxy-3-t-butylamino)propoxy-3,4-dihydrocarbostyril having the formula ##EQU5##
Claim 2
Independent Claim 35 words
A method for preventing blood platelet aggregation and minimizing blood platelet adhesion comprising applying in vitro to blood or in vivo to mammals afflicted with thrombosis an effective amount of 5-(hydroxy-3-t-butylamino)propoxy-3,4-dihydrocarbostyril having the formula ##EQU5##
Claim 3
Dependent Claim 30 words
The method of claim 1 wherein the dihydrocarbostyril compound is present in the blood in an effective amount of from about 10 - 5 to about 10 - 11 M.
Claim 4
Dependent Claim 20 words
The method according to claim 2, wherein said effective amount ranges from 10 - 8 to 10 - 10 M.
Claim 5
Independent Claim 36 words
A method for treating thrombosis to prevent blood platelet aggregation and to minimize blood platelet adhesion in a subject afflicted therewith comprising administering a therapeutically effective amount of 5-(hydroxy-3-t-butylamino)propoxy-3,4-dihydrocarbostyril having the formula ##EQU6## to said subject.
Claim 6
Independent Claim 36 words
A method for treating thrombosis to prevent blood platelet aggregation and to minimize blood platelet adhesion in a subject afflicted therewith comprising administering a therapeutically effective amount of 5-(hydroxy-3-t-butylamino)propoxy-3,4-dihydrocarbostyril having the formula ##EQU6## to said subject.
Claim 7
Dependent Claim 30 words
The method of claim 4 wherein the dihydrocarbostyril compound is present in the blood in an effective amount of from about 10 - 5 to about 10 - 11 M.
Claim 8
Dependent Claim 20 words
The method according to claim 5, wherein said effective amount ranges from 10 - 8 to 10 - 10 M.
Claim 9
Dependent Claim 17 words
The method according to claim 4 wherein 5 to 10 mg per subject per day is administered.

References Cited (Backward Citations)

US3351525A Cited
US3514459A Cited
US3813399A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-07-13 1980-01-12 1980-07-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-07-13 1984-01-12 1984-07-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-07-13 1988-01-12 1988-07-13 $7700.00 Window Closed / Lapsed

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