Patent US1921286A successfully refreshed from Google Patents.
Patent US2609841A successfully refreshed from Google Patents.
Patent US2861013A successfully refreshed from Google Patents.
Patent US3969468A successfully refreshed from Google Patents.
US3969468A
Expired / Lapsed
US
⏱️ 0.0 years remaining
2-Amino-1,2,3,4-tetrahydronaphthalene derivatives
Assignee: KH Neochem Co Ltd
•
Filing: 1973-10-29
•
Granted: 1976-07-13
•
Expires: 1993-10-29
Abstract
Abstract 6,7-Benzomorphan derivatives, which are useful as unaddictive analgesics, are prepared from aromatic aminoketones through several steps of reactions. Most of the intermediates are new compounds. Process for preparing 2-benzyl-1,2,5,6-tetrahydropyridine derivatives which are known as intermediates for the preparation of 6,7-benzomorphan derivatives is also disclosed.
Inventors
- 👤 Kentaro Tamaki
- 👤 Kyoichi Fujii
- 👤 Seiichi Yada
- 👤 Shiro Kudo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 13:47
CPC Classifications
C; C07; C07D; C07D221/00; C07D221/02; C07D221/22; C07D221/26; C07D211/00; C07D211/04; C07D211/68; C07D211/70
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
178 words
A compound represented by the formula: ##SPC8## wherein R 1 is a hydrogen atom, a hydroxy group, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a benzyloxy group or an alkanoyloxy group having 1 to 4 carbon atoms; R 2 is a hydrogen atom, an alkyl group having 1 to 8 carbon atoms which is either substituted or unsubstituted, the substituent being a phenyl group, a benzoyl group, ##SPC9## group, =O group or ##EQU10## group, a cycloalky group having 3 to 6 carbon atoms, a cycloalkylalkyl group having 4 to 8 carbon atoms or an alkyenyl group having 3 to 8 carbon atoms which is either substituted or unsubstituted, the substituent being a chlorine atom or a bromine atom; R 3 and R 4 are the same or different and are alkyl groups having 1 to 4 carbon atoms; R 5 is a hydrogen atom or a benzyl group; and Y is an alkoxy group having 1 to 4 carbon atoms, a phenoxy group or a benzyloxy group.
Claim 2
Dependent Claim
178 words
A compound represented by the formula: ##SPC8## wherein R 1 is a hydrogen atom, a hydroxy group, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a benzyloxy group or an alkanoyloxy group having 1 to 4 carbon atoms; R 2 is a hydrogen atom, an alkyl group having 1 to 8 carbon atoms which is either substituted or unsubstituted, the substituent being a phenyl group, a benzoyl group, ##SPC9## group, =O group or ##EQU10## group, a cycloalky group having 3 to 6 carbon atoms, a cycloalkylalkyl group having 4 to 8 carbon atoms or an alkyenyl group having 3 to 8 carbon atoms which is either substituted or unsubstituted, the substituent being a chlorine atom or a bromine atom; R 3 and R 4 are the same or different and are alkyl groups having 1 to 4 carbon atoms; R 5 is a hydrogen atom or a benzyl group; and Y is an alkoxy group having 1 to 4 carbon atoms, a phenoxy group or a benzyloxy group.
Claim 3
Dependent Claim
8 words
A compound according to claim 1, namely 1,2,3,4-tetrahydro-2-(N-methyl)amino-3,4-dimethyl-4-(β-ethoxy)ethylnaphthalene.
Claim 4
Dependent Claim
8 words
A compound according to claim 1, namely 1,2,3,4-tetrahydro-2-(N-methyl)amino-3,4-dimethyl-4-(β-methoxy)-ethylnaphthalene.
Claim 5
Dependent Claim
8 words
The compound according to claim 1, namely 1,2,3,4-tetrahydro-2-(N-methyl)amino-3,4-dimethyl-4-(β-ethoxy)ethyl-6-methoxynaphthalene.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-07-13 | 1980-01-12 | 1980-07-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-07-13 | 1984-01-12 | 1984-07-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-07-13 | 1988-01-12 | 1988-07-13 | $7700.00 | Window Closed / Lapsed |