Patent US3968277A successfully refreshed from Google Patents.
US3968277A
Expired / Lapsed
US
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Process for coating solid particles with a digestive tract-soluble film
Assignee: Zenyaku Kogyo KK
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Filing: 1974-02-20
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Granted: 1976-07-06
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Expires: 1994-02-20
Abstract
Abstract A coating process and apparatus for manufacturing of solid particles with digestive tracts-soluble film by rolling water-containing solid particles at high speed, adding a coating liquid and drying them simultaneously.
Inventors
- 👤 Muneaki Takase
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 19:46
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; A61K9/2893; A61J; A61J3/00; A61J3/005; A61K9/48; A61K9/50; A61K9/5089
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
144 words
A process for coating solid particles with a digestive tract-soluble film which comprises causing solid particles having a water content in the range of from 15 to 30% by weight of water to said particles to roll by a rotating disk rotating at a sufficient speed to provide a peripheral speed of from 200 to 450 meters per minute and applying a coating solution containing a digestive tract-soluble material selected from the group consisting of dialkylamino-ethyl methacrylate-alkylmethacrylate copolymers, alkylvinyl pyridine-methacrylic acid-alkyl acrylate copolymers, alkyl methacrylate-methacrylic acid copolymers, polyvinylacetal dialkylamino-acetate, and dicarboxylic acid halfester of cellulose acetate in a mixed solvent of at least two solvents selected from the group consisting of lower alcohols, lower ketones and lower halogenated hydrocarbons to said rolling particles and developing a digestive tract-soluble film on said particles while subjecting said particles to heated gas to evaporate said solvent therefrom.
Claim 2
Dependent Claim
144 words
A process for coating solid particles with a digestive tract-soluble film which comprises causing solid particles having a water content in the range of from 15 to 30% by weight of water to said particles to roll by a rotating disk rotating at a sufficient speed to provide a peripheral speed of from 200 to 450 meters per minute and applying a coating solution containing a digestive tract-soluble material selected from the group consisting of dialkylamino-ethyl methacrylate-alkylmethacrylate copolymers, alkylvinyl pyridine-methacrylic acid-alkyl acrylate copolymers, alkyl methacrylate-methacrylic acid copolymers, polyvinylacetal dialkylamino-acetate, and dicarboxylic acid halfester of cellulose acetate in a mixed solvent of at least two solvents selected from the group consisting of lower alcohols, lower ketones and lower halogenated hydrocarbons to said rolling particles and developing a digestive tract-soluble film on said particles while subjecting said particles to heated gas to evaporate said solvent therefrom.
Claim 3
Dependent Claim
33 words
The process for coating solid particles with stomach soluble film according to claim 1, wherein said coating solution comprises dialkylaminoethyl methacrylate-alkyl methacrylate copolymer in mixed solvent of lower ketone and lower halogenated hydrocarbon.
Claim 4
Dependent Claim
31 words
The process for coating solid particles with stomach-soluble film according to claim 1, wherein said coating solution comprises dialkylaminoethyl methacrylate-alkyl methacrylate copolymer in mixed solvent of lower ketone and lower alcohol.
Claim 5
Dependent Claim
30 words
The process for coating solid particles with stomach-soluble film according to claim 1, wherein said coating solution comprises polyvinylacetal dialkylaminoacetate in mixed solvent of lower ketone and lower halogenated hydrocarbon.
Claim 6
Dependent Claim
29 words
The process for coating solid particles with stomach-soluble film according to claim 1, wherein said coating solution comprises polyvinylacetal dialkylaminoacetate in mixed solvent of lower ketone and lower alcohol.
Claim 7
Dependent Claim
31 words
The process for coating solid particles with intestine-soluble film according to claim 1, wherein said coating solution comprises alkyl methacrylate-methacrylic acid copolymer in mixed solvent of lower ketone and lower alcohol.
Claim 8
Dependent Claim
33 words
The process for coating solid particles with intestine-soluble film according to claim 1, wherein said coating solution comprises dicarboxylic acid halfester of cellulose acetate in mixed solvent of lower ketone and lower alcohol.
Claim 9
Dependent Claim
33 words
The process for coating solid particles with gastro-intestine-soluble film according to claim 1, wherein said coating solution comprises alkyl vinyl pyridine-methacrylic acid-alkyl acrylate copolymer in mixed solvent lower halogenated hydrocarbon and lower alcohol.
Claim 10
Dependent Claim
31 words
The process of claim 1 wherein the solid particles are sensitive to water and they are pretreated with a protective coating, the necessary water being added simultaneously with the coating solution.
Claim 11
Dependent Claim
48 words
The process of claim 1 wherein the digestive tract-soluble film forming solute is present in an amount of from 5 to 25% and the temperature of the heated gas is from about 45° to 60°C, and wherein said coating operation is performed for less than about 35 minutes.
Claim 12
Dependent Claim
68 words
The process of claim 1, wherein the mixed solvent is a mixture of a lower ketone and lower halogenated hydrocarbon or lower alcohol with a mixing ratio of lower ketone to lower alcohol or halogenated hydrocarbon of between 9:1 to 3:7 or a mixture of a lower alcohol and lower halogenated hydrocarbon having a mixing ratio of lower alcohol to lower halogenated hydrocarbon of between 1:9 and 9:1.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-07-06 | 1980-01-05 | 1980-07-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-07-06 | 1984-01-05 | 1984-07-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-07-06 | 1988-01-05 | 1988-07-06 | $7700.00 | Window Closed / Lapsed |