Patent US3966596A successfully refreshed from Google Patents.
US3966596A
Expired / Lapsed
US
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High performance, cation-exchange chromatography on surface-sulfonated compositions
Assignee: Dow Chemical Co
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Filing: 1975-03-10
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Granted: 1976-06-29
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Expires: 1995-03-10
Abstract
Abstract A process for high performance, cation-exchange chromatography employing a cation-exchange composition comprising synthetic resin particles of about 5 to about 200 microns particle size, said synthetic resin particles being cross-linked to from about 0.25 to about 5% and surface-sulfonated to a calculated depth of about 100 to about 300 Angstroms is disclosed.
Inventors
- 👤 Timothy S. Stevens
- 👤 Hamish Small
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 20:21
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/96; B; B01; B01J; B01J39/00; B01J39/26; G01N30/02; G01N30/50; G01N30/52; G01N2030/524; G01N2030/525; G01N2030/965; G01N30/26; G01N30/38; G01N30/46; G01N30/461
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
85 words
A process for chromatographic separation of cations comprising: a. passing a fluid mixture comprising the cations through a bed comprising synthetic resin particles of about 5 microns to about 200 microns particle size, said synthetic resin particles being cross-linked to from about 0.25 percent to about 5 percent and surface-sulfonated to a calculated depth of about 100 Angstroms to about 300 Angstroms; and b. eluting the bed with an eluent which differentially removes cations which are attracted to surface-sulfonation sites on the synthetic resin particles.
Claim 2
Dependent Claim
85 words
A process for chromatographic separation of cations comprising: a. passing a fluid mixture comprising the cations through a bed comprising synthetic resin particles of about 5 microns to about 200 microns particle size, said synthetic resin particles being cross-linked to from about 0.25 percent to about 5 percent and surface-sulfonated to a calculated depth of about 100 Angstroms to about 300 Angstroms; and b. eluting the bed with an eluent which differentially removes cations which are attracted to surface-sulfonation sites on the synthetic resin particles.
Claim 3
Dependent Claim
17 words
A process described in claim 1 wherein the synthetic resin particles consist essentially of a poly(vinylaromatic) polymer.
Claim 4
Dependent Claim
22 words
A process described in claim 1 wherein the synthetic resin particles are of about 20 microns to about 100 microns particle size.
Claim 5
Dependent Claim
22 words
A process described in claim 1 wherein the synthetic resin particles are cross-linked to from about 1 percent to about 3.5 percent.
Claim 6
Dependent Claim
25 words
A process described in claim 1 wherein the synthetic resin particles are surface-sulfonated to a calculated depth of about 150 Angstroms to about 250 Angstroms.
Claim 7
Dependent Claim
45 words
A process described in claim 1 wherein the synthetic resin particles consist essentially of styrene-divinylbenzene copolymer which is cross-linked to from about 1 percent to about 3.5 percent and wherein said synthetic resin particles are of about 20 microns to about 100 microns particle size.
Claim 8
Dependent Claim
40 words
A process described in claim 6 wherein the synthetic resin particles are surface-sulfonated to a calculated depth of about 150 Angstroms to about 250 Angstroms and the sytrene-divinylbenzene copolymer is cross-linked to from about 1.5 percent to about 2.5 percent.
Claim 9
Dependent Claim
30 words
A process described in claim 1 wherein the fluid mixture comprises a liquid solution of the cations and sulfonate groups, prior to step (a), are predominately in the acid form.
Claim 10
Dependent Claim
15 words
A process described in claim 8 wherein the liquid solution comprises sodium and potassium cations.
Claim 11
Dependent Claim
56 words
A process described in claim 8 wherein the synthetic resin particles consist essentially of styrene-divinylbenzene copolymer which is cross-linked to from about 1.5 percent to about 2.5 percent and said synthetic resin particles are surface-sulfonated to a calculated depth of about 150 Angstroms to about 250 Angstroms and the eluent comprises an aqueous hydrochloric acid solution.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-29 | 1979-12-29 | 1980-06-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-29 | 1983-12-29 | 1984-06-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-29 | 1987-12-29 | 1988-06-29 | $7700.00 | Window Closed / Lapsed |