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US3960667A
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Antibiotic A23187 and process for preparation thereof
Assignee: Eli Lilly and Co
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Filing: 1975-07-08
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Granted: 1976-06-01
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Expires: 1995-07-08
Abstract
Abstract Antibiotic A23187 and process for production thereof by submerged aerobic culture of Streptomyces chartreusis NRRL 3882. The antibiotic demonstrates antimicrobial activity and exhibits ionophorous properties, with a specificity for divalent cations.
Inventors
- 👤 Richard M. Gale
- 👤 Calvin E. Higgens
- 👤 Marvin M. Hoehn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 21:28
CPC Classifications
C; C07; C07D; C07D413/00; C07D413/14; C07G; C07G11/00; Y; Y10; Y10S; Y10S435/00; Y10S435/803; Y10S435/8215; Y10S435/822; Y10S435/886; Y10S435/893
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
52 words
The method for producing the antibiotic A-23187 of the formula ##SPC2## which comprises cultivating Streptomyces chartreusis NRRL 3882 in a culture medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic fermentation conditions until a substantial amount of antibiotic A-23187 is produced by said organism in said culture medium.
Claim 2
Independent Claim
52 words
The method for producing the antibiotic A-23187 of the formula ##SPC2## which comprises cultivating Streptomyces chartreusis NRRL 3882 in a culture medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic fermentation conditions until a substantial amount of antibiotic A-23187 is produced by said organism in said culture medium.
Claim 3
Dependent Claim
57 words
A method of producing the antibiotic of claim 1 which comprises cultivating Streptomyces chartreusis NRRL 3882 in a culture medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions until a substantial amount of antibiotic A23187 is produced by said organism in said culture medium and recovering antibiotic A23187 from the mycelial growth.
References Cited (Backward Citations)
US2928844A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-01 | 1979-12-01 | 1980-06-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-01 | 1983-12-01 | 1984-06-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-01 | 1987-12-01 | 1988-06-01 | $7700.00 | Window Closed / Lapsed |