Patent US3957758A successfully refreshed from Google Patents.
US3957758A
Expired / Lapsed
US
⏱️ 0.0 years remaining
6-acyl derivatives of aminopenicillanic acid
Assignee: Hoffmann La Roche Inc
•
Filing: 1974-07-30
•
Granted: 1976-05-18
•
Expires: 1994-07-30
Abstract
Abstract Compounds represented by the following formula ##EQU1## wherein A is a substituted or unsubstituted heterocyclic radical and T is a C 2 -C 5 alkyl, alkenyl, cyclopropylmethyl, cyclobutylmethyl or cyclopentyl group A process for their preparation and novel intermediates therefor are disclosed. These compounds are useful antibiotics.
Inventors
- 👤 Andre Furlenmeier
- 👤 Peter Quitt
- 👤 Karl Vogler
- 👤 Paul Lanz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 23:34
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/82; C07D307/84; C07D307/02; C07D307/04; C07D307/18; C07D307/24; C07D307/34; C07D307/56; C07D307/68
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
80 words
Compounds represented by the formula ##EQU8## wherein A is pyridyl, 1-oxido-pyridyl, tetrahydropyranyl, pyrimidinyl, benzofuranyl, indolyl, quinolyl or isoquinolyl which may be substituted with halogen, oxo, hydroxy, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, C 1 -C 3 alkoxy charbonyl or C 1 -C 3 alkanoylamino groups, and T is a C 2 -C 5 alkyl, or C 2 -C 5 alkenyl, cyclopropyl methyl, cyclobutylmethyl or cyclopentyl group and pharmaceutically acceptable salts are hydrated forms of said salts.
Claim 2
Dependent Claim
80 words
Compounds represented by the formula ##EQU8## wherein A is pyridyl, 1-oxido-pyridyl, tetrahydropyranyl, pyrimidinyl, benzofuranyl, indolyl, quinolyl or isoquinolyl which may be substituted with halogen, oxo, hydroxy, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, C 1 -C 3 alkoxy charbonyl or C 1 -C 3 alkanoylamino groups, and T is a C 2 -C 5 alkyl, or C 2 -C 5 alkenyl, cyclopropyl methyl, cyclobutylmethyl or cyclopentyl group and pharmaceutically acceptable salts are hydrated forms of said salts.
Claim 3
Dependent Claim
19 words
Compounds in accordance with claim 1 wherein A is selected from the group consisting of 3-pyridyl, 2-methyl-4-pyridyl, pyrazinyl, tetrahydro-4-pyranyl.
Claim 4
Dependent Claim
20 words
Compounds in accordance with claim 1 wherein T is an alkyl or alkenyl group containing 4 or 5 carbon atoms.
Claim 5
Dependent Claim
12 words
Compounds in accordance with claim 1 wherein T is an isobutyl group.
Claim 6
Dependent Claim
14 words
Compounds in accordance with claim 1 wherein the group ##EQU9## has the R configuration.
References Cited (Backward Citations)
US3803128A
Cited
US3839322A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-05-18 | 1979-11-17 | 1980-05-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-05-18 | 1983-11-17 | 1984-05-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-05-18 | 1987-11-17 | 1988-05-18 | $7700.00 | Window Closed / Lapsed |