Patent US4641846A successfully refreshed from Google Patents.
Patent US3954976A successfully refreshed from Google Patents.
US3954976A
Expired / Lapsed
US
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Pharmaceutical compositions for inhibiting absorption of cholesterol
Assignee: Procter and Gamble Co
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Filing: 1973-12-14
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Granted: 1976-05-04
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Expires: 1993-12-14
Abstract
Abstract Pharmaceutical compositions for inhibiting the absorption of cholesterol comprising effective unit dosage amounts of a polyol fatty acid ester having at least four fatty acid ester groups; and a method for treating and/or preventing hypercholesterolemia in an animal comprising systematically administering to such animal successive therapeutically effective doses of said polyol fatty acid ester.
Inventors
- 👤 Fred Hugh Mattson
- 👤 Robert Anthony Volpenhein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 17:32
CPC Classifications
C; C07; C07H; C07H13/00; C07H13/02; C07H13/04; C07H13/06; A; A61; A61K; A61K31/00; A61K31/21; A61K31/215; A61K31/22; A61K31/23; A61K31/70
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
73 words
A pharmaceutical composition in effective unit dosage amounts for inhibiting the absorption of cholesterol comprising from about 0.1 gram to about 5 grams of a polyol fatty acid ester having at least four fatty acid esters groups, wherein the polyol is selected from the group consisting of sugars and sugar alcohols containing from four to eight hydroxyl groups and wherein each fatty acid group has from about eight to about 22 carbon atoms.
Claim 2
Dependent Claim
73 words
A pharmaceutical composition in effective unit dosage amounts for inhibiting the absorption of cholesterol comprising from about 0.1 gram to about 5 grams of a polyol fatty acid ester having at least four fatty acid esters groups, wherein the polyol is selected from the group consisting of sugars and sugar alcohols containing from four to eight hydroxyl groups and wherein each fatty acid group has from about eight to about 22 carbon atoms.
Claim 3
Dependent Claim
17 words
A composition in accordance with claim 1 wherein the hydroxy groups of the polyol are all esterified.
Claim 4
Dependent Claim
19 words
A composition in accordance with claim 1 containing from about 0.5 gram to about 2 grams per unit dosage.
Claim 5
Dependent Claim
14 words
A composition in accordance with claim 5 wherein the esterified polyol is sucrose octaoleate.
Claim 6
Independent Claim
77 words
A method for treating hypercholesterolemia by inhibiting the absorption of cholesterol comprising systemically administering to an animal susceptible to or afflicted with hypercholesterolemia successive therapeutically effective doses of a polyol fatty acid ester having at least 4 fatty acid esters groups, wherein the polyol is selected from the group consisting of sugars and sugar alcohols containing from four to eight hydroxyl groups and wherein each fatty acid group has from about eight to about 22 carbon atoms.
Claim 7
Independent Claim
77 words
A method for treating hypercholesterolemia by inhibiting the absorption of cholesterol comprising systemically administering to an animal susceptible to or afflicted with hypercholesterolemia successive therapeutically effective doses of a polyol fatty acid ester having at least 4 fatty acid esters groups, wherein the polyol is selected from the group consisting of sugars and sugar alcohols containing from four to eight hydroxyl groups and wherein each fatty acid group has from about eight to about 22 carbon atoms.
Claim 8
Dependent Claim
15 words
The method of claim 5 wherein the hydroxy groups of the polyol are all esterified.
Claim 9
Dependent Claim
23 words
The method of claim 6 wherein the doses are unit doses containing from about 0.5 gram to about 5 grams per unit dose.
Claim 10
Dependent Claim
19 words
The method of claim 7 wherein the unit doses are from about 0.5 to 2 grams per unit dose.
Claim 11
Dependent Claim
12 words
The method of claim 8 wherein the esterified polyol is sucrose octaoleate.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-05-04 | 1979-11-03 | 1980-05-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-05-04 | 1983-11-03 | 1984-05-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-05-04 | 1987-11-03 | 1988-05-04 | $7700.00 | Window Closed / Lapsed |