3-Hydrazino-cycloalkyl[c]pyridazines

Abstract

Abstract This invention provides aminopyridazine derivatives of formula I, wherein R1 is amino, or an R3 -N=C ANGLE R4 group, wherein each of R3 and R4 is alkyl of 1 to 4 carbon atoms, or R3 and R4 together with the carbon atom to which they are bound, form a cycloalkylidene radical of 5 to 12 carbon atoms, R2 is hydrogen or methyl, A is a -(CH2)n- group, WHEREIN N IS 0 OR AN INTEGER FROM 1 TO 7, OR AN >N-CO-R5 group, WHEREIN R5 is alkyl or alkenyl of 1 to 16 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, 1-adamantyl, or a -(CH2)m-R6 group, WHEREIN M IS 0 OR AN INTEGER FROM 1 TO 4, AND R6 is phenyl; phenyl monosubstituted by fluorine, chlorine, bromine, alkyl or alkoxy of 1 to 4 carbon atoms, alkylmercapto of 1 to 4 carbon atoms, or phenyl; phenyl substituted by two or three substituents of the group chlorine, alkyl or alkoxy of 1 to 4 carbon atoms; diphenylmethyl, the phenyl rings of which may be monosubstituted by fluorine, chlorine, bromine, alkyl or alkoxy of 1 to 4 carbon atoms; or naphthyl, OR AN -OR7 group, WHEREIN R7 is alkyl or alkenyl of 1 to 4 carbon atoms, or phenyl, phenylalkyl or phenylalkenyl which may be monosubstituted on the phenyl ring by chlorine, alkyl or alkoxy of 1 to 4 carbon atoms, and in which the alkylene or alkenylene chain is of 1 to 4 carbon atoms, AND R8 and R9 are each hydrogen or alkyl of 1 to 4 carbon atoms, AND ACID ADDITION SALTS THEREOF.

Inventors

• 👤 Erhard Schenker

Bibliographic Details