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Patent US3953467A successfully refreshed from Google Patents.
US3953467A
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Pyrazole derivatives and process for preparing the same
Assignee: Maruko Pharmaceutical Co Ltd
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Filing: 1974-04-17
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Granted: 1976-04-27
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Expires: 1994-04-17
Abstract
Abstract Pyrazole derivatives represented by the formula WHEREIN R, X, R2 and R3 are hereinafter defined, which are useful as analgesics and anti-inflammatory agents and a process for preparing the pyrazole derivatives are disclosed.
Inventors
- 👤 Hajime Fujimura
- 👤 Mikio Hori
- 👤 Osamu Ootani
- 👤 Sachio Ohno
- 👤 Tadashi Kitamikado
- 👤 Kiyoshi Kato
- 👤 Mitsuaki Nagasaka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 03:43
CPC Classifications
C; C07; C07D; C07D231/00; C07D231/02; C07D231/10; C07D231/14; C07D231/18; C07D231/20; C07D231/22
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
136 words
Pyrazole compounds represented by the formula ##SPC4## wherein R represents an alkyl group of 1 to 4 carbon atoms, X represents a mono- or di-substituted phenyl group wherein the substituents may be the same or different and each represents an alkyl group of 1 to 4 carbon atoms, an alkoxy group of 1 to 4 carbon atoms, a trifluoromethyl group, a nitro group, an amino group or a halogen atom; or a substituted or unsubstituted benzyl group wherein the substituent is a halogen atom, R 2 represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms and R 3 represents a hydrogen atom, a hydroxyalkyl group of 1 to 4 carbon atoms, an alkyl group of 1 to 4 carbon atoms or a substituted aminoalkyl group of 1 to 4 carbon atoms.
Claim 2
Dependent Claim
136 words
Pyrazole compounds represented by the formula ##SPC4## wherein R represents an alkyl group of 1 to 4 carbon atoms, X represents a mono- or di-substituted phenyl group wherein the substituents may be the same or different and each represents an alkyl group of 1 to 4 carbon atoms, an alkoxy group of 1 to 4 carbon atoms, a trifluoromethyl group, a nitro group, an amino group or a halogen atom; or a substituted or unsubstituted benzyl group wherein the substituent is a halogen atom, R 2 represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms and R 3 represents a hydrogen atom, a hydroxyalkyl group of 1 to 4 carbon atoms, an alkyl group of 1 to 4 carbon atoms or a substituted aminoalkyl group of 1 to 4 carbon atoms.
Claim 3
Dependent Claim
5 words
1-(p-Tolyl)-3-N,N-dimethylcarbamoyl-5-methoxypyrazole according to claim 1.
Claim 4
Dependent Claim
5 words
1-(m-Trifluoromethylphenyl)-3-N,N-dimethylcarbamoyl-5-n-butoxypyrazole according to claim 1.
Claim 5
Dependent Claim
5 words
1-(m-Chlorophenyl)-3-N,N-dimethylcarbamoyl-5-methoxypyrazole according to claim 1.
Claim 6
Dependent Claim
5 words
1-(m-Chlorophenyl)-3-carbamoyl-5-methoxypyrazole according to claim 1.
Claim 7
Dependent Claim
5 words
1-(p-Chlorobenzyl)-3-N-methylcarbamoyl-5-methoxypyrazole according to claim 1.
Claim 8
Dependent Claim
5 words
1-(m-Chlorophenyl)-3-N-methylcarbamoyl-5-methoxypyrazole according to claim 1.
Claim 9
Dependent Claim
5 words
1-(m-Chlorophenyl)-3-N-ethylcarbamoyl-5-methoxypyrazole according to claim 1.
Claim 10
Dependent Claim
5 words
1-(m-Bromophenyl)-3-N-methylcarbamoyl-5-methoxypyrazole according to claim 1.
Claim 11
Dependent Claim
5 words
1-(m-Bromophenyl)-3-N-ethylcarbamoyl-5-methoxypyrazole according to claim 1.
Claim 12
Dependent Claim
5 words
1-(m-Bromophenyl)-3-N,N-dimethylcarbamoyl-5-methoxypyrazole according to claim 1.
Claim 13
Dependent Claim
80 words
Pyrazole compounds represented by the formula ##SPC5## wherein R represents a straight or branched chain alkyl group having 1 to 4 carbon atoms, R 2 represents a hydrogen atom or a methyl group, R 3 represents a methyl group, and X represents a m- or p-monosubstituted phenyl group wherein the substitutent in a chlorine atom, a bromine atom or a trifluoromethyl group, or X represents a p-monosubstituted benzyl group wherein the substitutent is a chlorine atom or a bromine atom.
Claim 14
Dependent Claim
80 words
Pyrazole compounds represented by the formula ##SPC5## wherein R represents a straight or branched chain alkyl group having 1 to 4 carbon atoms, R 2 represents a hydrogen atom or a methyl group, R 3 represents a methyl group, and X represents a m- or p-monosubstituted phenyl group wherein the substitutent in a chlorine atom, a bromine atom or a trifluoromethyl group, or X represents a p-monosubstituted benzyl group wherein the substitutent is a chlorine atom or a bromine atom.
Claim 15
Dependent Claim
21 words
A compound of claim 12, wherein R is a methyl group and X is a m-chlorophenyl group or a m-bromophenyl group.
Claim 16
Dependent Claim
11 words
A compound of claim 12, wherein X is a m-chlorophenyl group.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-04-27 | 1979-10-27 | 1980-04-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-04-27 | 1983-10-27 | 1984-04-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-04-27 | 1987-10-27 | 1988-04-27 | $7700.00 | Window Closed / Lapsed |