Patent US4225431A successfully refreshed from Google Patents.
Patent US3950516A successfully refreshed from Google Patents.
US3950516A
Expired / Lapsed
US
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Process for preparing cirramycin A1
Assignee: Bristol Myers Co
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Filing: 1971-11-18
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Granted: 1976-04-13
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Expires: 1991-11-18
Abstract
Abstract The specification discloses a process for preparing cirramycin A 1 which comprises fermentation of cirramycin B 1 and subsequent conversion thereof to cirramycin A 1 by incubation in the presence of cane molasses.
Inventors
- 👤 Takeo Miyaki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 08:37
CPC Classifications
C; C07; C07G; C07G11/00
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
88 words
A process for the production of cirramycin A 1 which comprises producing cirramycin B 1 by cultivation of a strain of Streptomyces cirratus in an aqueous carbohydrate solution containing a nitrogenous nutrient under anerobic conditions until substantial antibiotic potency is produced in the broth, separating the cirramycin B 1 from said broth, and incubating the separated cirramycin B 1 in an aqueous substrate containing at least about 2 per cent cane molasses at a temperature sufficient to cause substantial conversion to cirramycin A 1 until substantial conversion results.
Claim 2
Dependent Claim
88 words
A process for the production of cirramycin A 1 which comprises producing cirramycin B 1 by cultivation of a strain of Streptomyces cirratus in an aqueous carbohydrate solution containing a nitrogenous nutrient under anerobic conditions until substantial antibiotic potency is produced in the broth, separating the cirramycin B 1 from said broth, and incubating the separated cirramycin B 1 in an aqueous substrate containing at least about 2 per cent cane molasses at a temperature sufficient to cause substantial conversion to cirramycin A 1 until substantial conversion results.
Claim 3
Dependent Claim
29 words
A process according to claim 1 wherein the cirramycin B 1 separated from the broth is added to the substrate as an aqueous extract of cirramycin B 1 .
Claim 4
Dependent Claim
21 words
A process according to claim 1 wherein cirramycin B 1 is added to the substrate as solid cirramycin B 1 .
Claim 5
Dependent Claim
33 words
A process according to claim 1 wherein the strain of Streptomyces cirratus is ATCC 21731, the incubation temperature is about 37° C., and the substrate is a 2% aqueous solution of cane molasses.
References Cited (Backward Citations)
US3159540A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-04-13 | 1979-10-13 | 1980-04-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-04-13 | 1983-10-13 | 1984-04-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-04-13 | 1987-10-13 | 1988-04-13 | $7700.00 | Window Closed / Lapsed |