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US3950324A
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D-glucose-1-0-nicotinoyl-2-deoxy-2-nictinamido derivatives
Assignee: Hoffmann La Roche Inc
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Filing: 1975-01-09
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Granted: 1976-04-13
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Expires: 1995-01-09
Abstract
Abstract A novel class of glucose derivatives, i.e., 3,4,6-tri-o-acyl-2-deoxy-2-nicotinamido-1-0-nicotinoyl-D-glucopyranoses are disclosed. These compounds are pharmaceutically active and are useful as plasma lypid lowering agents.
Inventors
- 👤 Karl Friedrich Gey
- 👤 Joseph Kiss
- 👤 Hans Lengsfeld
- 👤 Pierre-Charles Wyss
- 👤 Willy Schuep
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 20:05
CPC Classifications
C; C07; C07H; C07H13/00; C07H13/02; C07H13/10
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
34 words
A glucose derivative of the formula ##SPC5## wherein R is lower alkanoyl, (lower alkoxy)-(lower alkanoyl) or benzoyl which may be substituted by C 1 -C 6 alkyl, C 1 -C 6 alkoxy or halogen.
Claim 2
Dependent Claim
34 words
A glucose derivative of the formula ##SPC5## wherein R is lower alkanoyl, (lower alkoxy)-(lower alkanoyl) or benzoyl which may be substituted by C 1 -C 6 alkyl, C 1 -C 6 alkoxy or halogen.
Claim 3
Dependent Claim
11 words
The glucose derivative of claim 1 wherein R is lower alkanoyl.
Claim 4
Dependent Claim
10 words
The glucose derivative of claim 2 which is 3,4,6-tri-O-acetyl-2-deoxy-2-nicotinamido-1-O-nicotinoyl-β ,D-glucopyranose.
Claim 5
Dependent Claim
10 words
The glucose derivative of claim 2 which is 3,4,6-tri-O-propionyl-2-deoxy-2-nicotinamido-1-O-nicotinoyl-β ,D-glucopyranose.
Claim 6
Dependent Claim
27 words
A glucose derivative of claim 1 wherein R is benzoyl which may be substituted by C 1 -C 6 alkyl, C 1 -C 6 alkoxy or halogen.
Claim 7
Dependent Claim
10 words
The glucose derivative of claim 5 which is 3,4,6-tri-O-benzoyl-2-deoxy-2-nicotinamido-1-O-nicotinoyl-β ,D-glucopyranose.
References Cited (Backward Citations)
US2918462A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-04-13 | 1979-10-13 | 1980-04-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-04-13 | 1983-10-13 | 1984-04-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-04-13 | 1987-10-13 | 1988-04-13 | $7700.00 | Window Closed / Lapsed |