US3944590A
Expired / Lapsed
US
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Process for the temporary protection of amino groups in peptide syntheses
Assignee: Novartis Corp
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Filing: 1974-08-29
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Granted: 1976-03-16
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Expires: 1994-08-29
Abstract
Abstract Temporary protection of amino groups by the group of the formula I ##EQU1## in which R 1 represents lower alkyl, R 2 lower alkyl or phenyl and R 3 phenyl, and wherein the phenyl radicals are unsubstituted or substituted by lower alkyl, phenyl or lower alkylphenyl groups. This is a division of application Ser. No. 239,721, filed Mar. 30, 1972 (now U.S. Pat. No. 3,875,207), which is in turn a continuation-in-part of application Ser. No. 698,118 filed Jan. 16, 1968 (now abandoned).
Inventors
- 👤 Beat Iselin
- 👤 Peter Sieber
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 10:56
CPC Classifications
C; C07; C07K; C07K1/00; C07K1/06; C07K1/061; C07K1/063; C07K1/064; C07K5/00; C07K5/04; C07K5/06; C07K5/06086; C07K5/08; C07K5/0802; C07K5/0812; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
47 words
A compound of the formula II ##EQU4## in which R 1 is lower alkyl, R 2 is lower alkyl or phenyl and R 3 is phenyl and wherein phenyl is unsubstituted or substituted by lower alkyl, phenyl or lower alkylphenyl and X stands for phenyloxy or p-nitrophenyloxy.
Claim 2
Dependent Claim
47 words
A compound of the formula II ##EQU4## in which R 1 is lower alkyl, R 2 is lower alkyl or phenyl and R 3 is phenyl and wherein phenyl is unsubstituted or substituted by lower alkyl, phenyl or lower alkylphenyl and X stands for phenyloxy or p-nitrophenyloxy.
Claim 3
Dependent Claim
32 words
A compound of claim 1, wherein R 1 and R 2 each represents a methyl or ethyl group, R 3 has the same meaning as in claim 1, and X is phenyloxy.
Claim 4
Dependent Claim
26 words
A compound of claim 1, wherein R 3 represents a phenyl, tolyl or biphenylyl group, and R 2 stands for lower alkyl, and X is phenyloxy.
Claim 5
Dependent Claim
26 words
A compound of claim 1, wherein R 1 stands for methyl or ethyl, R 2 and R 3 each stands for phenyl, and X is phenyloxy.
Claim 6
Dependent Claim
17 words
A compound of claim 1, wherein the ##EQU5## group is the 2-phenyl-isopropyloxycarbonyl group or the 1,1-diphenylethyloxycarbonyl group.
Claim 7
Dependent Claim
17 words
A compound of claim 1, wherein the ##EQU6## group is the 2-para-tolylisopropyloxycarbonyl group, and X is phenyloxy.
Claim 8
Dependent Claim
17 words
A compound of claim 1, wherein the ##EQU7## group is the 2-(para-biphenylyl)-isopropyloxycarbonyl group, and X is phenyloxy.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-03-16 | 1979-09-15 | 1980-03-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-03-16 | 1983-09-15 | 1984-03-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-03-16 | 1987-09-15 | 1988-03-16 | $7700.00 | Window Closed / Lapsed |