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US3941787A Expired / Lapsed US ⏱️ 0.0 years remaining

1,4-Disubstituted-5,8-methano-tetrahydro-quinazolinones

Assignee: Sandoz Inc
•
Filing: 1974-07-22
•
Granted: 1976-03-02
•
Expires: 1994-07-22
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Abstract

Abstract Anti-inflammatory agents of the formula I:

Inventors

  • 👤 William G. Salmond

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 17:50
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/70

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 139 words
A compound of the formula ##SPC15## wherein: R is lower alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms or cycloalkylalkyl of 4 to 10 carbon atoms in which the cycloalkyl is of 3 to 8 carbon atoms and the alkyl of 1 to 3 carbon atoms, R' is a radical of the formula ##SPC16## in which Y and Y' are the same or different and represent hydrogen, halo of atomic weight of 18 to 36, alkyl having from 1 to 2 carbon atoms, alkoxy having from 1 to 2 carbon atoms, or one of Y and Y' is trifluoromethyl while the other is hydrogen, or a radical of the formula ##SPC17## in which Y" is hydrogen, halo of atomic weight of from 18 to 36 or alkyl of 1 to 3 carbon atoms.
Claim 2
Dependent Claim 139 words
A compound of the formula ##SPC15## wherein: R is lower alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms or cycloalkylalkyl of 4 to 10 carbon atoms in which the cycloalkyl is of 3 to 8 carbon atoms and the alkyl of 1 to 3 carbon atoms, R' is a radical of the formula ##SPC16## in which Y and Y' are the same or different and represent hydrogen, halo of atomic weight of 18 to 36, alkyl having from 1 to 2 carbon atoms, alkoxy having from 1 to 2 carbon atoms, or one of Y and Y' is trifluoromethyl while the other is hydrogen, or a radical of the formula ##SPC17## in which Y" is hydrogen, halo of atomic weight of from 18 to 36 or alkyl of 1 to 3 carbon atoms.
Claim 3
Dependent Claim 13 words
A compound of claim 1 in which R' is phenyl or substituted phenyl.
Claim 4
Dependent Claim 10 words
A compound of claim 2 in which R' is phenyl.
Claim 5
Dependent Claim 10 words
A compound of claim 1 in which R is alkyl.
Claim 6
Dependent Claim 10 words
A compound of claim 4 in which R is isopropyl.
Claim 7
Dependent Claim 10 words
A compound of claim 2 in which R is isopropyl.
Claim 8
Dependent Claim 10 words
The compound of claim 6 in which R' is phenyl.
Claim 9
Dependent Claim 10 words
The compound of claim 6 in which R' is 4-fluorophenyl.
Claim 10
Dependent Claim 10 words
A compound of claim 1 in which R is cyclopropylmethyl.
Claim 11
Dependent Claim 8 words
The compound of claim 6 which is 1-isopropyl-4-phenyl-5,8-methano-5,6,7,8-tetrahydro-2(1H)-quinazolinone.

References Cited (Backward Citations)

US3563990A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-03-02 1979-09-01 1980-03-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-03-02 1983-09-01 1984-03-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-03-02 1987-09-01 1988-03-02 $7700.00 Window Closed / Lapsed

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