US3936439A
Expired / Lapsed
US
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2,6-Diaminonebularine derivatives
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1973-11-30
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Granted: 1976-02-03
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Expires: 1993-11-30
Abstract
Abstract Novel 2,6-diaminonebularine derivatives of the formula WHEREIN R is a phenyl or cyclohexyl group which may be substituted with lower alkyl, lower alkoxy or halogen, and pharmaceutically acceptable salts thereof, exhibit excellent pharmacological acitivity such as strong and prolonged coronary dilating and platelet aggregation inhibitory actions.
Inventors
- 👤 Ryuji Marumoto
- 👤 Yoshio Yoshioka
- 👤 Mikio Honjo
- 👤 Katsuyoshi Kawazoe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 01:07
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
33 words
A 2,6-diaminonebularine derivative of the formula ##SPC8## wherein R is a phenyl or cyclohexyl group which may be substituted with lower alkyl, lower alkoxy or halogen, or pharmaceutically acceptable mineral acid salts thereof.
Claim 2
Dependent Claim
33 words
A 2,6-diaminonebularine derivative of the formula ##SPC8## wherein R is a phenyl or cyclohexyl group which may be substituted with lower alkyl, lower alkoxy or halogen, or pharmaceutically acceptable mineral acid salts thereof.
Claim 3
Dependent Claim
15 words
The 2,6-diaminonebularine derivative according to claim 1, wherein the mineral acid salt is a hydrochloride.
Claim 4
Dependent Claim
24 words
The 2,6-diaminonebularine derivative according to claim 1, wherein R is a phenyl group which may be substituted with lower alkyl, lower alkoxy or halogen.
Claim 5
Dependent Claim
24 words
The 2,6-diaminonebularine derivative according to claim 3, wherein R is a phenyl group substituted with a lower alkyl having up to four carbon atoms.
Claim 6
Dependent Claim
24 words
The 2,6-diaminonebularine derivative according to claim 3, wherein R is a phenyl group substituted with a lower alkoxy having up to four carbon atoms.
Claim 7
Dependent Claim
16 words
The 2,6-diaminonebularine derivative according to claim 3, wherein R is a phenyl group substituted with halogen.
Claim 8
Dependent Claim
24 words
The 2,6-diaminonebularine derivative according to claim 1, wherein R is a cyclohexyl group which may be substituted with lower alkyl, lower alkoxy or halogen.
Claim 9
Dependent Claim
24 words
The 2,6-diaminonebularine derivative according to claim 7, wherein R is a cyclohexyl group substituted with a lower alkyl having up to four carbon atoms.
Claim 10
Dependent Claim
12 words
The 2,6-diaminonebularine derivative according to claim 1, which is N 2 -phenyl-2,6-diaminonebularine.
Claim 11
Dependent Claim
12 words
The 2,6-diaminonebularine derivative according to claim 1, which is N 2 -(p-methylphenyl)-2,6-diaminonebularine.
Claim 12
Dependent Claim
12 words
The 2,6-diaminonebularine derivative according to claim 1, which is N 2 -(p-methoxyphenyl)2,6-diaminonebularine.
Claim 13
Dependent Claim
12 words
The 2,6-diaminonebularine derivative according to claim 1, which is N 2 -(p-chlorophenyl)-2,6-diaminonebularine.
Claim 14
Dependent Claim
12 words
The 2,6-diaminonebularine derivative according to claim 1, which is N 2 -cyclohexyl-2,6-diaminonebularine.
Claim 15
Dependent Claim
12 words
The 2,6-diaminonebularine derivative according to claim 1, which is N 2 -(p-methylcyclohexyl)-2,6-diaminonebularine.
Claim 16
Dependent Claim
13 words
A 2,6-diaminonebularine derivative according to claim 1 which is N 2 -phenyl-2,6-diaminonebularine hydrochloride.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-02-02 | 1979-08-04 | 1980-02-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-02-02 | 1983-08-04 | 1984-02-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-02-02 | 1987-08-04 | 1988-02-03 | $7700.00 | Window Closed / Lapsed |