US3933827A
Expired / Lapsed
US
⏱️ 0.0 years remaining
9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-B]carbazoles
Assignee: Hoffmann La Roche Inc
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Filing: 1974-10-29
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Granted: 1976-01-20
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Expires: 1994-10-29
Abstract
Abstract 9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazoles of the formula WHEREIN R1 is acyl and R2 is hydrogen or lower alkyl, are described. The end products actively inhibit the growth of transplantable tumors, and are therefore useful as cytostatic agents.
Inventors
- 👤 Arnold Brossi
- 👤 Robert William Guthrie
- 👤 Richard Wightman Kierstead
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 21:59
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/04
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
52 words
A compound of the formula ##SPC6## wherein R 1 is alkanoyl of 1 to 18 carbon atoms, alicyclic alkanoyl of 3 to 12 carbon atoms, benzoyl, 3,4,5-trimethoxybenzoyl, 4-chlorobenzoyl, or 4-methylbenzoyl and R 2 is hydrogen or lower alkyl of 1 to 7 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
52 words
A compound of the formula ##SPC6## wherein R 1 is alkanoyl of 1 to 18 carbon atoms, alicyclic alkanoyl of 3 to 12 carbon atoms, benzoyl, 3,4,5-trimethoxybenzoyl, 4-chlorobenzoyl, or 4-methylbenzoyl and R 2 is hydrogen or lower alkyl of 1 to 7 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
19 words
A compound in accordance with claim 1, wherein R 1 is lower alkanoyl of 1 to 18 carbon atoms.
Claim 4
Dependent Claim
12 words
A compound in accordance with claim 2, wherein R 1 is acetyl.
Claim 5
Dependent Claim
8 words
A compound in accordance with claim 1, 9-acetoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole.
Claim 6
Dependent Claim
8 words
A compound in accordance with claim 1, 9-propionyloxy-5,11-dimethyl-6-pyrido[4,3-b]carbazole.
Claim 7
Dependent Claim
8 words
A compound in accordance with claim 1, 9-(2-methylpropionyloxy)-5,11-dimethyl-6H-pyrido[4,3-b]carbazole.
Claim 8
Dependent Claim
8 words
A compound in accordance with claim 1, 9-hexanoyloxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole.
Claim 9
Dependent Claim
8 words
a compound in accordance with claim 1, 9-dodecanoyloxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole.
Claim 10
Dependent Claim
8 words
A compound in accordance with claim 1, 9-stearoyloxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole.
Claim 11
Dependent Claim
8 words
A compound in accordance with claim 1, 9-(1-adamantoyloxy)-5,11-dimethyl-6H-pyrido[4,3-b]carbazole.
Claim 12
Dependent Claim
8 words
A compound in accordance with claim 1, 9-acetoxy-5,6,11-trimethyl-6H-pyrido[4,3-b]carbazole.
Claim 13
Dependent Claim
8 words
A compound in accordance with claim 1, 9-benzoyl-5,11-dimethyl-6H-pyrido[4,3-b]carbazole.
Claim 14
Dependent Claim
8 words
A compound in accordance with claim 1, 9-hexanoyloxy-5,6,11-trimethyl-6H-pyrido[4,3-b]carbazole.
References Cited (Backward Citations)
US3772306A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-01-19 | 1979-07-21 | 1980-01-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-01-19 | 1983-07-21 | 1984-01-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-01-19 | 1987-07-21 | 1988-01-20 | $7700.00 | Window Closed / Lapsed |