US3772306A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,2,4a,5,6,8,9,14,14a,14b-decahydrobenz(a)indolo(2,3-g)quinolizin-3(4h)-ones
Assignee: Warner Lambert Co LLC
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Filing: 1971-11-26
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Granted: 1973-11-13
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Expires: 1991-11-26
Abstract
Abstract COMPOUNDS OF THE FORMULA ARE DISCLOSED: 3-(O=),9-R,X-1,2,3,4,4A,5,6,8,9,14,14A,14B-DODECAHYDRO- BENZ(A)INDOLO(2,3-G)QUINOLIZINE WHEREIN X IS HYDROGEN, LOWER ALKYL, LOWER ALKOXY, HALOGEN, AMINO, N,N-DISUBSTITUTED AMINO, ETHERIFIED MERCAPTO, NITRO AND HYDROXYL; AND R IS HYDROGEN, LOWER ALKYL, ARALKYL SUBSTITUTED ARALKYL AND ACYL. THESE COMPOUNDS ARE PREPARED BY THE CYCLIZATION OF A 1,2,3,4-TETRAHYDRO-1(INDOL-3-YLMETHYL)-6-METHOXYISOQUINOLINE WITH FORMALDEHYDE TO GIVE A HEXAHYDRO-3-METHOXYBENZE(A)INDOLO(2,3-G)QUINOLIZINE, FOLLOWED BY REDUCTION AND HYDROLYSIS RESPECTIVELY. THESE COMPOUNDS ARE USEFUL AS ANTI-HYPERTENSIVE AGENTS.
Inventors
- 👤 G Morrison
- 👤 J Shavel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 22:17
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/12; C07D471/14
Claims Analysis
Total Claims: 0
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References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-11-12 | 1977-05-14 | 1977-11-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-11-12 | 1981-05-14 | 1981-11-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-11-12 | 1985-05-14 | 1985-11-13 | $7700.00 | Window Closed / Lapsed |