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N-aminomethyl-2-amino(and 2-amino-methyl)-2-(2-quinolyl)-thioacetamides

Assignee: GlaxoSmithKline LLC
•
Filing: 1974-09-18
•
Granted: 1976-01-20
•
Expires: 1994-09-18
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Abstract

Abstract The compounds are N-aminomethyl-2-amino(and 2-aminomethyl)-2-heterocyclic-thioacetamides which are inhibitors of gastric acid secretion.

Inventors

  • 👤 L. Martin Brenner
  • 👤 Bernard Loev

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 19:15
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/04; C07D295/12; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; C07D239/00; C07D239/02; C07D239/24; C07D239/26; C07D241/00; C07D241/02; C07D241/10; C07D241/12; C07D413/00; C07D413/02; C07D413/12

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 40 words
A compound of the formula: ##EQU5## in which m is 0 or 1; R 1 is 2-quinolyl; and R 2 and R 3 are di-lower alkylamino, N-lower Alkyl-N-phenylamino, piperidino, pyrrolidino or morpoholino or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim 40 words
A compound of the formula: ##EQU5## in which m is 0 or 1; R 1 is 2-quinolyl; and R 2 and R 3 are di-lower alkylamino, N-lower Alkyl-N-phenylamino, piperidino, pyrrolidino or morpoholino or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim 40 words
A compounds of claim 1 in which m is 0 or 1 and R 2 is dimethylamino, diethylamino, piperidino or pyrrolidino or m is 1 and R 2 is morpholino, and R 3 is di-lower alkylamino, piperidino, pyrrolidino or morpholino.
Claim 4
Dependent Claim 9 words
A compound of claim 1, said compound being 3-morpholino-N-morpholinomethyl-2-(2-quinolyl)thiopropanamide.
Claim 5
Dependent Claim 9 words
A compound of claim 1, said compound being 2-dimethylamino-N-morpholinomethyl-2-(2-quinolyl)thioacetamide.

References Cited (Backward Citations)

US3726878A Cited
US3876645A Cited
US3660592A Cited
US3749728A Cited
US3880860A Cited
US3740409A Cited
US3882126A Cited
US3825547A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-01-19 1979-07-21 1980-01-20 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-01-19 1983-07-21 1984-01-20 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-01-19 1987-07-21 1988-01-20 $7700.00 Window Closed / Lapsed

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