Patent US3929793A successfully refreshed from Google Patents.
US3929793A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Certain piperazine-containing indole compounds
Assignee: Roche Diagnostics GmbH
•
Filing: 1974-06-28
•
Granted: 1975-12-30
•
Expires: 1994-06-28
Abstract
Abstract New indole compound of the formula: WHEREIN R1 is hydrogen or alkyl; R2 is hydrogen, alkoxycarbonyl or carboxyl; R3 is hydrogen, halogen, alkyl, alkoxy or alkylthio; and A is hydrogen or hydroxyl; AND THE PHARMACOLOGICALLY COMPATIBLE SALTS THEREOF; ARE OUTSTANDINGLY EFFECTIVE IN INDUCING BLOOD PRESSURE DEPRESSION AND THUS ARE ANTI-HYPERTENSIVE AGENTS.
Inventors
- 👤 Alfred Popelak
- 👤 Wolfgang Kampe
- 👤 Max Thiel
- 👤 Karl Dietmann
- 👤 Gisbert Sponer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 20:27
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/12; C07D401/06; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; C07D209/00; C07D209/02; C07D209/04; C07D209/43; C07D241/00; C07D241/02; C07D241/04; C07D295/00; C07D295/04; C07D295/12; C07D403/00; C07D403/02; C07D403/12
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
5 words
INDOLE COMPOUND OF THE FORMULA:
Claim 2
Dependent Claim
5 words
INDOLE COMPOUND OF THE FORMULA:
Claim 3
Dependent Claim
11 words
Indole compound as claimed in claim 1 wherein R1 is hydrogen.
Claim 4
Dependent Claim
17 words
Indole compound as claimed in claim 1 wherein R1 is alkyl of up to 3 carbon atoms.
Claim 5
Dependent Claim
11 words
Indole compound as claimed in claim 1 wherein R2 is hydrogen.
Claim 6
Dependent Claim
17 words
Indole compound as claimed in claim 1 wherein R2 is alkoxycarbonyl of up to 5 carbon atoms.
Claim 7
Dependent Claim
11 words
Indole compound as claimed in claim 1 wherein R2 is carboxyl.
Claim 8
Dependent Claim
11 words
Indole compound as claimed in claim 1 wherein R3 is hydrogen.
Claim 9
Dependent Claim
11 words
Indole compound as claimed in claim 1 wherein R3 is halogen.
Claim 10
Dependent Claim
17 words
Indole compound as claimed in claim 1 wherein R3 is alkyl of up to 3 carbon atoms.
Claim 11
Dependent Claim
17 words
Indole compound as claimed in claim 1 wherein R3 is alkoxy of up to 4 carbon atoms.
Claim 12
Dependent Claim
17 words
Indole compound as claimed in claim 1 wherein R3 is alkylthio of up to 4 carbon atoms.
Claim 13
Dependent Claim
11 words
Indole compound as claimed in claim 1 wherein A is hydrogen.
Claim 14
Dependent Claim
11 words
Indole compound as claimed in claim 1 wherein A is hydroxyl.
Claim 15
Dependent Claim
9 words
Indole compound as claimed in claim 1 designated 5-(2-hydroxy-3-(4-(2-methoxyphenyl)-piperazinyl-1)-propoxy)-indole.
Claim 16
Dependent Claim
9 words
Indole compound as claimed in claim 1 designated 5-(2-hydroxy-3-(4-(2-methoxyphenyl)-piperazinyl-1)-propoxy)-1-methyl-indole.
Claim 17
Dependent Claim
9 words
Indole compound as claimed in claim 1 designated 4-(2-hydroxy-3-(4-(2-methyl-phenyl)-piperazinyl-1)-propoxy)-indole.
Claim 18
Dependent Claim
9 words
Indole compound as claimed in claim 1 designated 5-(2-hydroxy-3-(4-(2-methylthiophenyl)-piperazinyl-1)-propoxy)-indole.
Claim 19
Dependent Claim
10 words
Indole compound as claimed in claim 1 designated ethyl 4-(3-(4-(2-methoxyphenyl)-piperazinyl-1)-propoxy)-indole-2-carboxylate.
Claim 20
Dependent Claim
10 words
Indole compound as claimed in claim 1 designated 4-(3-(4-(2-methoxyphenyl)-piperazinyl-1)-propoxy)-indole-2-carboxylic acid.
References Cited (Backward Citations)
US3509163A
Cited
US3787411A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-12-29 | 1979-06-30 | 1979-12-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-12-29 | 1983-06-30 | 1983-12-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-12-29 | 1987-06-30 | 1987-12-30 | $7700.00 | Window Closed / Lapsed |