Patent US3923989A successfully refreshed from Google Patents.
US3923989A
Expired / Lapsed
US
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Nitro substituted picolinonitriles as anti-bacterial and anti-fungal agents
Assignee: Sandoz AG
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Filing: 1974-08-20
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Granted: 1975-12-02
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Expires: 1994-08-20
Abstract
Abstract Nitro substituted picolinonitriles, in particular 3-nitropicolinonitrile, have been found to be useful as anti-bacterial and anti-fungal agents.
Inventors
- 👤 Paul L Anderson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 22:57
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/78; C07D213/84
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
33 words
A METHOD OF TREATING BACTERIA AND FUNGI, WHICH COMPRISES INTERNALLY OR TOPICALLY ADMINISTERING TO A MAMMMAL IN NEED OF SAID TREATMENT AN ANTI-BACTERIAL OR ANTI-FUNGAL EFFECTIVE AMOUNT OF A COMPOUND OF THE FORMULA:
Claim 2
Independent Claim
33 words
A METHOD OF TREATING BACTERIA AND FUNGI, WHICH COMPRISES INTERNALLY OR TOPICALLY ADMINISTERING TO A MAMMMAL IN NEED OF SAID TREATMENT AN ANTI-BACTERIAL OR ANTI-FUNGAL EFFECTIVE AMOUNT OF A COMPOUND OF THE FORMULA:
Claim 3
Dependent Claim
25 words
A method according to claim 1 wherein said compound is administered internally at a daily dose of from about 100 milligrams to about 6.0 grams.
Claim 4
Dependent Claim
34 words
A method according to claim 1 wherein the compound is administered in a unit dosage form comprising said compound to the extent of from about 25 milligrams to about 3000 grams per unit dosage.
Claim 5
Dependent Claim
24 words
A method according to claim 1 wherein said compound is administered internally at a daily dose of from about 250 milligrams to about2.5 grams.
Claim 6
Dependent Claim
34 words
A method according to claim 1 wherein the compound is administered in a unit dosage form comprising said compound to the extent of from about 62.5 milligrams to about 1.25 grams per unit dosage.
Claim 7
Dependent Claim
11 words
A method according to claim 1 wherein said compound is 3-nitro-picolinonitrile.
Claim 8
Dependent Claim
11 words
The method according to claim 1 wherein said compound is 4-nitro-picolinonitrile.
Claim 9
Dependent Claim
29 words
A method according to claim 1 wherein said compound is administered topically in an topical composition containing said compound in a concentration by weight of 0.5 to 30 percent.
Claim 10
Dependent Claim
23 words
A method according to claim 8 wherein the topical composition contains said compound in a concentration by weight of 0.5 to 10 percent.
Claim 11
Dependent Claim
11 words
The method according to claim 8 wherein said compound is 3-nitro-picolinonitrile.
Claim 12
Dependent Claim
11 words
The method according to claim 8 wherein said compound is 4-nitro-picolinonitrile.
Claim 13
Dependent Claim
28 words
A pharmaceutical composition in solid or sterile solution form useful in treating bacteria and fungus infections topically, comprising as the active ingredient thereof a compound of the formula:
Claim 14
Dependent Claim
28 words
A pharmaceutical composition in solid or sterile solution form useful in treating bacteria and fungus infections topically, comprising as the active ingredient thereof a compound of the formula:
Claim 15
Dependent Claim
22 words
A pharmaceutical composition according to claim 12 wherein said compound is present at a concentration by weight of 0.5 to 10 percent.
Claim 16
Dependent Claim
12 words
The pharmaceutical composition of claim 12 wherein the active ingredient is 3-nitro-picolinonitrile.
Claim 17
Dependent Claim
12 words
The pharmaceutical composition of claim 12 wherein the active ingredient is 4-nitro-picolinonitrile.
Claim 18
Dependent Claim
10 words
The pharmaceutical composition of claim 12 which is an ointment.
Claim 19
Dependent Claim
11 words
The pharmaceutical composition of claim 12 which is a topical cream.
Claim 20
Dependent Claim
28 words
A pharmaceutical composition in solid or sterile solution form useful in treating bacteria and fungus infections internally, comprising as the active ingredient thereof a compound of the formula:
Claim 21
Dependent Claim
28 words
A pharmaceutical composition in solid or sterile solution form useful in treating bacteria and fungus infections internally, comprising as the active ingredient thereof a compound of the formula:
Claim 22
Dependent Claim
30 words
A pharmaceutical composition according to claim 18 in which said compound is present in said composition in an amount by weight of from about 62.5 milligrams to about 1,250 milligrams.
Claim 23
Dependent Claim
13 words
The pharmaceutical composition according to claim 18 wherein the active ingredient is 3-nitro-picolinonitrile.
Claim 24
Dependent Claim
13 words
The pharmaceutical composition according to claim 18, wherein the active ingredient is 4-nitro-picolinonitrile.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-12-01 | 1979-06-02 | 1979-12-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-12-01 | 1983-06-02 | 1983-12-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-12-01 | 1987-06-02 | 1987-12-02 | $7700.00 | Window Closed / Lapsed |