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US3923982A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for preventing trace element deficiency in animals and compositions for carrying out said process

Assignee: Institut National de la Recherche Agronomique
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Filing: 1973-09-19
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Granted: 1975-12-02
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Expires: 1993-09-19
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Abstract

Abstract A process for preventing trace element deficiency in animals and injectable compositions are described. The trace element compounds are put in suspension in an oil, such as purified olive oil. The said compounds are in an insoluble, non ionizable form, which is solubilized slowly by a moderate inflammatory reaction. In the case of copper, a suitable form is powdered copper or copper oxide. For zinc, zinc oxide or zinc is used. For manganese, the oxide Mn3O4 is prefered. The compositions are administered to ovines, or bovines by intramuscular or subcutaneous injections.

Inventors

  • 👤 Michel Lamand
  • 👤 Nee Astier Claudine Lab
  • 👤 Remy Roux
  • 👤 Paul Chagnaud

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 22:21
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 77 words
A METHOD FOR CONTROLLING TRACE-METAL DEFICIENCY IN BOVINE AND OVINE ANIMALS, COMPRISING THE STEP OF INJECTING, BY INTRAMUSCULAR OR SUBCUTANEOUS ROUTE, TO SUCH ANIMALS HAVING SUCH DIFICIENCY AN EFFECTIVE AMOUNT OF A COMPOSITION IN THE FORM OF A SUSPENSION CONTAINING SAID TRACE-METALS IN A VISCOUS AND APYROGENOUS EXCIPIENT, THE SUSPENDED TRACE-METAL BEING PRESENT AS THE FREE METAL OR AN OXIDE THEREOF, BEING NON-SOLUBLE IN AQUEOUS MEDIA, NON-IONIZABLE AND CAPABLE OF SLOW RELEASE AFTER INTRAMUSCULAR OR SUBCUTANEOUS INJECTION.
Claim 2
Independent Claim 77 words
A METHOD FOR CONTROLLING TRACE-METAL DEFICIENCY IN BOVINE AND OVINE ANIMALS, COMPRISING THE STEP OF INJECTING, BY INTRAMUSCULAR OR SUBCUTANEOUS ROUTE, TO SUCH ANIMALS HAVING SUCH DIFICIENCY AN EFFECTIVE AMOUNT OF A COMPOSITION IN THE FORM OF A SUSPENSION CONTAINING SAID TRACE-METALS IN A VISCOUS AND APYROGENOUS EXCIPIENT, THE SUSPENDED TRACE-METAL BEING PRESENT AS THE FREE METAL OR AN OXIDE THEREOF, BEING NON-SOLUBLE IN AQUEOUS MEDIA, NON-IONIZABLE AND CAPABLE OF SLOW RELEASE AFTER INTRAMUSCULAR OR SUBCUTANEOUS INJECTION.
Claim 3
Dependent Claim 28 words
The method of claim 1, wherein said excipient is a purified vegetable oil selected from the group consisting of olive oil, peanut oil, corn oil and sunflower oil.
Claim 4
Dependent Claim 12 words
The method of claim 1, wherein said excipient is purified almond oil.
Claim 5
Dependent Claim 30 words
The method of claim 1, wherein the suspended trace-metal compound is selected from the group consisting of copper, zinc and manganese in the form of fine powders of free metals.
Claim 6
Dependent Claim 22 words
The method of claim 1, wherein the suspended trace-element compound is selected from the group consisting of CuO, ZnO, MnO2 and Mn3O4.
Claim 7
Dependent Claim 26 words
The method of claim 1, wherein the trace-metal compound is present as a powder having an average particle size of about 1 to 3 Mu .
Claim 8
Dependent Claim 43 words
The method of claim 4, wherein the trace-metal is copper in a concentration in the suspension between about 10 mg and 15 mg/ml of excipient, the injected dosage being from 5 to 10 ml according the animal being treated and the weight thereof.
Claim 9
Dependent Claim 42 words
The method of claim 4, wherein the trace-metal is zinc in a concentration in the suspension between about 40 and 100 mg/ml of excipient, the injected dosage being from 5 to 10 ml according the animal being treated and the weight thereof.
Claim 10
Dependent Claim 43 words
The method of claim 5, wherein the trace-metal compound is CuO in a concentration in the suspension between about 10 and 20 mg/ml of excipient, the injected dosage being from 5 to 10 ml according the aNimal being treated and the weight thereof.
Claim 11
Dependent Claim 43 words
The method of claim 5, wherein the trace-metal compound is ZnO in a concentration in the suspension between about 45 and 120 mg/ml of excipient, the injected dosage being from 5 to 10 ml according the animal being treated and the weight thereof.
Claim 12
Dependent Claim 43 words
The method of claim 5, wherein the trace-metal compound is Mn3O4 in a concentration in the suspension between about 30 and 100 mg/ml of excipient, the injected dosage being from 5 to 10 ml according the animal being treated and the weight thereof.

References Cited (Backward Citations)

US2476351A Cited
US2951014A Cited
US3712291A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-12-01 1979-06-02 1979-12-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-12-01 1983-06-02 1983-12-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-12-01 1987-06-02 1987-12-02 $7700.00 Window Closed / Lapsed

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