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US3920835A Expired / Lapsed US ⏱️ 0.0 years remaining

Treatment of disturbed keratinization

Assignee: Individual
•
Filing: 1974-02-25
•
Granted: 1975-11-18
•
Expires: 1994-02-25
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Abstract

Abstract A treatment to alleviate the symptoms of diseases characterized by defects in keratinization consisting of the topical application of an ointment or lotion containing one or more lower aliphatic compounds having from two to about six carbon atoms, and preferably having Alpha -carbon functionality is disclosed. The compounds include Alpha -hydroxy acids, keto acids and esters thereof, and 3-hydroxybutyric acid. The therapeutic composition may include one or more of the compounds present in a total of from one to twenty percent in either a water or alcohol solution or an ointment. Topical application to affected areas has been found to achieve a complete remission of dandruff, acne and palmar and plantar hyperkeratosis.

Inventors

  • 👤 Scott Eugene J Van
  • 👤 Ruey J Yu

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 13:27
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/185; A61K31/19; A61K31/21; A61K31/215; A61K31/22; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/36; A61K8/365; A61Q; A61Q19/00; A61Q5/00; A61Q5/006

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 77 words
A METHOD OF ALLEVIATING THE SYMPTOMS OF ACNE COMPRISING TOPICALLY APPLYING AN EFFECTIVE AMOUNT OF A MEDICINAL COMPOSITION TO THE INVOLVED PORTIONS OF THE HUMAN BODY, SAID COMPOSITION COMPRISING FROM ABOUT 1% TO ABOUT 20% BY WEIGHT OF A COMPOUND SELECTED FROM THE GROUP CONSISTING OF GLYCOLIC ACID, CITRIC ACID, MALIC ACID, TARTRONIC ACID, TARTARIC ACID, GLYCURONIC ACID, PYRUVIC ACID, ETHYL PYRUVATE, METHYL PYRUVATE, 2HYDROXYISOBUTYRIC ACID, AND 3-HYDROXY BUTYRIC ACID IN ADMIXTURE WITH A PHARMACEUTICALLY ACCEPTABLE CARRIER.
Claim 2
Independent Claim 77 words
A METHOD OF ALLEVIATING THE SYMPTOMS OF ACNE COMPRISING TOPICALLY APPLYING AN EFFECTIVE AMOUNT OF A MEDICINAL COMPOSITION TO THE INVOLVED PORTIONS OF THE HUMAN BODY, SAID COMPOSITION COMPRISING FROM ABOUT 1% TO ABOUT 20% BY WEIGHT OF A COMPOUND SELECTED FROM THE GROUP CONSISTING OF GLYCOLIC ACID, CITRIC ACID, MALIC ACID, TARTRONIC ACID, TARTARIC ACID, GLYCURONIC ACID, PYRUVIC ACID, ETHYL PYRUVATE, METHYL PYRUVATE, 2HYDROXYISOBUTYRIC ACID, AND 3-HYDROXY BUTYRIC ACID IN ADMIXTURE WITH A PHARMACEUTICALLY ACCEPTABLE CARRIER.
Claim 3
Dependent Claim 18 words
The method of claim 1 wherein said compound is present in from 5% to about 10% by weight.
Claim 4
Dependent Claim 51 words
The method of claim 2 wherein said composition is an ointment containing said compound dissolved in about 1% to about 30% by volume of a solvent selected from the group consisting of water and ethanol, and admixed with an ointment base selected from the group consisting of petrolatum and hydrophilic ointment.
Claim 5
Dependent Claim 43 words
The method of claim 1 wherein said compound is dissolved in a mixture of water, ethanol, and propylene glycol, said ethanol being present in no more than about 70% by weight and propylene glycol present in no more than about 30% by weight.
Claim 6
Dependent Claim 23 words
The method of claim 4 wherein said liquid is an admixture of water, ethanol, and propylene glycol present in a ratio of 40:40:
Claim 7
Dependent Claim 1 words
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Claim 8
Dependent Claim 1 words
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References Cited (Backward Citations)

US3124506A Cited
US2118566A Cited
US3259545A Cited
US3666863A Cited
US3608086A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-11-17 1979-05-19 1979-11-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-11-17 1983-05-19 1983-11-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-11-17 1987-05-19 1987-11-18 $7700.00 Window Closed / Lapsed

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