Quinazoline compounds
Abstract
Abstract 2-(4''-SUBSTITUTED HOMOPIPERAZINO)-4-AMINO-6,7-DIMETHOXYQUINAZOLINES HAVING THE FOLLOWING CHEMICAL FORMULA (I): v,2/14 WHEREIN A represents a group selected from the following (i) and (ii): (I) R1-CO-: wherein R1 represents a lower alkyl group of C1-C4; phenyl group substituted with a halogen atom, methoxy group of methanesulfonyl group; and styryl group unsubstituted or ring substituted with a halogen atom, methoxy group or 3,4methylenedioxy group; or 2-furyl group, (II) R2-: R2 represents a lower alkyl group; benzyl group substituted with a halogen atom or methoxy group; or Beta -(2-pyridyl)ethyl group, AND THEIR PHARMACOLOGICALLY ACCEPTABLE ACID-ADDITION SALTS ARE PREPARED BY REACTING AT A 2-HOMOPIPERAZINO-4-AMINO-6,7-DIMETHOXYQUINAZOLINE WITH A REACTANT OF CHEMICAL FORMULA OF R1-COOH or its reactive derivative or a reactant of chemical formula of R2-X wherein X represents a halogen atom.
Inventors
- 👤 Tohru Takahashi
- 👤 Hachiro Sugimoto
Bibliographic Details
Claims Analysis
Total Claims: 6References Cited (Backward Citations)
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