US3919190A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Water insoluble antibiotic metal cellulose compounds and process of preparation
Assignee: Ranks Hovis McDougall Ltd
•
Filing: 1973-04-27
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Granted: 1975-11-11
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Expires: 1993-04-27
Abstract
Abstract A process for the preparation of a water insoluble antibiotic which process comprises reacting at pH 3 to 7 an antibiotic exhibiting antibacterial activity with a titanium, tin, zirconium, iron or vanadium derivative of cellulose or a derivative thereof. The antibiotic may be streptomycin, paromomycin, gentamycin, kanamycin, neomycin, polymyxin, ampicillin or natamycin.
Inventors
- 👤 Sidney Alan Barker
- 👤 John Frederick Kennedy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 16:15
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/61; A61K6/00; A61K6/50; A61K6/52; A61K6/60; A61K6/69
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
67 words
A PROCESS FOR THE PREPARATION OF AN ACTIVE WATER INSOLUBLE ANTIBIOTIC COMPRISING REACTING AT A PH BETWEEN 3 AND 7 AN ANTIBIOTIC EXHIBITING ENTIBACTERIAL ACTIVIY CONTAINING AT LEAST ONE AMINO GROUP SELECTED FROM THE GROUP CONSISTING OF STREPTOMYCIN, PAROMOMYCIN, GENTAMYCIN, KANAMYIC, NEOMYCIN, POLYMYXIN, AMPICILLIN AND NATAMYCIN WITH A METAL DERIVATIVE OF CELLULOSE, SAID METAL BEING SELECTED FROM THE GROUP CONSISTING OF TITANIUM, TIN, ZIROCONIUM, IRON AN VANADIUM.
Claim 2
Dependent Claim
67 words
A PROCESS FOR THE PREPARATION OF AN ACTIVE WATER INSOLUBLE ANTIBIOTIC COMPRISING REACTING AT A PH BETWEEN 3 AND 7 AN ANTIBIOTIC EXHIBITING ENTIBACTERIAL ACTIVIY CONTAINING AT LEAST ONE AMINO GROUP SELECTED FROM THE GROUP CONSISTING OF STREPTOMYCIN, PAROMOMYCIN, GENTAMYCIN, KANAMYIC, NEOMYCIN, POLYMYXIN, AMPICILLIN AND NATAMYCIN WITH A METAL DERIVATIVE OF CELLULOSE, SAID METAL BEING SELECTED FROM THE GROUP CONSISTING OF TITANIUM, TIN, ZIROCONIUM, IRON AN VANADIUM.
Claim 3
Dependent Claim
47 words
A process as claimed in claim 1 wherein said titanium, tin, zirconium, iron or vanadium derivative of cellulose is obtained by reaction of said cellulose with an aqueous solution of a metal salt selected from the group consisting of halides of titanium, tin, zirconium, iron or vanadium.
Claim 4
Dependent Claim
23 words
A process as claimed in claim 1 wherein the reaction is carried out at a pH of 4.5 for 1 hour at 4*C.
Claim 5
Dependent Claim
42 words
Active water-insoluble preparations of antibiotics exhibiting antibacterial activity containing at least one amino group selected from the group consisting of streptomycin, paromomycin, gentamycin, kanamycin, neomycin, polymyxin, ampicillin and natamycin chemically coupled to a titanate, zirconate, stannate, iron or vanadium derivative of cellulose.
Claim 6
Dependent Claim
42 words
Active water-insoluble preparations of antibiotics exhibiting antibacterial activity containing at least one amino group selected from the group consisting of streptomycin, paromomycin, gentamycin, kanamycin, neomycin, polymyxin, ampicillin and natamycin chemically coupled to a titanate, zirconate, stannate, iron or vanadium derivative of cellulose.
Claim 7
Dependent Claim
19 words
A water insoluble derivative of streptomycin chemically coupled to a titanium, tin, zirconium, iron, or vanadium derivative of cellulose.
Claim 8
Dependent Claim
19 words
A water insoluble derivative of streptomycin chemically coupled to a titanium, tin, zirconium, iron, or vanadium derivative of cellulose.
Claim 9
Dependent Claim
19 words
A water insoluble derivative of paromomycin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 10
Dependent Claim
19 words
A water insoluble derivative of paromomycin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 11
Dependent Claim
19 words
A water insoluble derivative of gentamycin chemically coUpled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 12
Dependent Claim
19 words
A water insoluble derivative of gentamycin chemically coUpled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 13
Dependent Claim
19 words
A water insoluble derivative of kanamycin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 14
Dependent Claim
19 words
A water insoluble derivative of kanamycin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 15
Dependent Claim
19 words
A water insoluble derivative of neomycin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 16
Dependent Claim
19 words
A water insoluble derivative of neomycin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 17
Dependent Claim
19 words
A water insoluble derivative of polymyxin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 18
Dependent Claim
19 words
A water insoluble derivative of polymyxin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 19
Dependent Claim
19 words
A water insoluble derivative of ampicillin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 20
Dependent Claim
19 words
A water insoluble derivative of ampicillin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 21
Dependent Claim
19 words
A water insoluble derivative of natamycin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
Claim 22
Dependent Claim
19 words
A water insoluble derivative of natamycin chemically coupled to a titanium, tin, zirconium, iron or vanadium derivative of cellulose.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-11-10 | 1979-05-12 | 1979-11-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-11-10 | 1983-05-12 | 1983-11-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-11-10 | 1987-05-12 | 1987-11-11 | $7700.00 | Window Closed / Lapsed |