Patent US3914283A successfully refreshed from Google Patents.
US3914283A
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Polymeric local anesthetic and anti-arrhythmic agents
Assignee: F Hoffmann La Roche AG
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Filing: 1973-12-10
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Granted: 1975-10-21
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Expires: 1993-12-10
Abstract
Abstract Polymers comprising repeating units of local anesthetic moieties covalently bonded by means of an amide linkage to a group derived from a carboxyl of a polymeric acid backbone exhibit local anesthetic and anti-arrhythmic activity similar to the parent moiety but of significantly longer duration.
Inventors
- 👤 Yoshiyuki Okamoto
- 👤 Jr Walter Franklin Riker
- 👤 Sidney Udenfriend
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 10:37
CPC Classifications
C; C08; C08F; C08F20/00; C08F20/02; C08F20/10; C08F20/34; C08F20/36; A; A61; A61K; A61K31/00; A61K31/74; A61K31/765; C08F8/00; C08F8/30; C08F8/32
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim
13 words
The compound of claim 1 wherein p is 0 and R is hydrogen.
Claim 4
Dependent Claim
25 words
The compound of claim 2 wherein An is selected from the group consisting of radicals derived from procaine, procaine amide or an aromatic amino-substituted lidocaine.
Claim 5
Dependent Claim
9 words
The compound of claim 1 wherein n is 0.
Claim 6
Dependent Claim
13 words
The compound of claim 4 wherein m is between about 10 and 20.
Claim 7
Dependent Claim
13 words
The compound of claim 4 wherein m is between about 300 and 400.
Claim 8
Dependent Claim
11 words
The compound of claim 1 wherein n is 1 or greater.
Claim 9
Dependent Claim
15 words
The compound of claim 7 wherein m + n is between about 10 and 20.
Claim 10
Dependent Claim
15 words
The compound of claim 7 wherein m + n is between about 300 and 400.
Claim 11
Dependent Claim
5 words
A compound of the formula
Claim 12
Dependent Claim
5 words
A compound of the formula
Claim 13
Dependent Claim
13 words
The compound of claim 10 wherein m is between about 10 and 20.
Claim 14
Dependent Claim
13 words
The compound of claim 10 wherein m is between about 300 and 400.
Claim 15
Dependent Claim
11 words
The compound of claim 11 wherein An is derived from procaine.
Claim 16
Dependent Claim
12 words
The compound of claim 11 wherein An is derived from procaine amide.
Claim 17
Dependent Claim
11 words
The compound of claim 11 wherein An is derived from m-aminolidocaine.
Claim 18
Dependent Claim
11 words
The compound of claim 11 wherein An is derived from p-aminolidocaine.
Claim 19
Dependent Claim
11 words
The compound of claim 12 wherein An is derived from procaine.
Claim 20
Dependent Claim
5 words
A compound of the formula
Claim 21
Dependent Claim
5 words
A compound of the formula
Claim 22
Dependent Claim
13 words
The compound of claim 18 wherein R is hydrogen and p is 0.
Claim 23
Dependent Claim
8 words
The compound of claim 19 which is acrylylprocaine.
Claim 24
Dependent Claim
9 words
The compound of claim 19 which is acrylylprocaine amide.
Claim 25
Dependent Claim
8 words
The compound of claim 19 which is acrylyl-m-aminolidocaine.
Claim 26
Dependent Claim
8 words
The compound of claim 19 which is acrylyl-p-aminolidocaine.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-10-20 | 1979-04-21 | 1979-10-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-10-20 | 1983-04-21 | 1983-10-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-10-20 | 1987-04-21 | 1987-10-21 | $7700.00 | Window Closed / Lapsed |