1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives

Claim 1

A COMPOUND SELECTED FROM: 1-R1-1,4-DIHYDRO-3(COOR)-4-OXO-5(OR 6)-R''-7-PY-QUINOLINE WHERE R1 NONTERTIARY LOWER-ALKYL, LOWER-HYDROXYALKYL OR LOWER-HALOALKYL, R IS HYDROGEN, NON-TERIARY LOWER-ALKYL OR CH2OAC WHERE AC IS LOWER-ALKANOL OR BENZOYL, R'' IS HALO, NON-TERTIARY LOWER-ALKYL OR LOWER-ALKOXY OR R'' IS HYDROGEN WHEN R IS CH2OAC, AND PY IS Q-1-(O)N-4(3 OR 2)-PYRIDYL, Q-1-Q''-4(3 OR 2)-PIPERIDYL OR 1-(LOWER-ALKYL)-1,2-DIHYDRO-2-OXO-4-PYRIDYL, WHERE N IS ZERO OF 1, Q IS FROM ZERO TO FOUR SUBSTITUENTS SELECTED FROM NON-TERTIARY LOWER-ALKYL WHERE TWO OF FOUR SAID SUBSTITUTENTS AT THE 3AND 5-POSITIONS OF 4-PYRIDYL CAN BE REPLACED BY LOWERCARBALKOXY OR CARBOXY, OR Q IS FROM ONE TO TWO SUBSTUENTS SELECTED FROM LOWER-ALKOXY, HALO, HYDROXY, LOWER-ALKANOYLOXY, HYDROXYMETHYL, FORMYL, CARBOXY AND LOWER-CARBALKOXY WHERE ONE OF THE TWO SAID SUBSTITENTS CAN BE REPLACED BY NON-TERIARY LOWER-ALKYL, OR Q IS A SINGLE SUBSTITUENT SELECTED FROM AMINOMETHYL, LOWER-ALKANOYALMINOMETHYL, AMINO, CYANO AND CARBAMYL, AND Q'' IS HYDROGEN OR NON-TERIARY LOWER-ALKYL, WHERE LOWER IN EACH OF LOWER-ALKYL, LOWERALKOXYL, LOWER-ALKANOYL AND ALKOXYL OF LOWER-CARBALKOXY DESIGNATES FROM ONE TO SIX CARBON ATOMS AND IN EACH OF LOWERHYDROXYALKYL AND LOWERHALOALKYL DESINGANTES FROM TWO TO SIX CARBON ATOMS, AND, A MEDICINALLY ACCEPTABLE SALT THEREOF.