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US3901655A Expired / Lapsed US ⏱️ 0.0 years remaining

Urine toxicology control

Assignee: IL Holding Spa
•
Filing: 1973-12-26
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Granted: 1975-08-26
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Expires: 1993-12-26
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Abstract

Abstract A lyophilized pooled normal human urine control for use in drug screening and analysis of human urine for drugs, which control is prepared from pooled normal human urine by treating said urine with a styrene-divinylbenzene copolymer resin to remove contaminants which interfere with said analysis followed by the addition of known amounts of drugs to the purified or contaminant free urine.

Inventors

  • 👤 Ravindra Shivprasad Shukla
  • 👤 Joseph Diago Pinto

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 21:38
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/96; Y; Y10; Y10S; Y10S436/00; Y10S436/901; Y10T; Y10T436/00; Y10T436/10

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 99 words
THE METHOD OF MAKING A LYOPHILIZED NORMAL HUMAN URINE DURG CONTROL FROM POOLED NORMAL HUMAN URINE FOR USE AS A CONTROL IN HUMAN URINE DRUG SCREENING AND ANALYSIS PROCEDURES WHICH COMPRISES: A. MIXING A WASHED STYRENE-DIVINYLBENZENE COPOLYMER RESIN AND HUMAN URINE TOGETHER IN THE RATIO OF ABOUT 5 GRAMS OF RESIN PER 100 ML. OF URINE FOR ABOUT ONE-HALF HOUR, B. SEPARATING THE RESIN TREATED URINE FROM SAID RESIN, C. FILTERING THE SEPARATED RESIN TREATED URINE THROUGH AN INFUSORIAL EARTH BED, D. ADDING KNOWN CONCENTRATIONS OF PURE DRUGS TO THE FILTERED URINE, AND E. LYOPHILIZING THE DRUG CONTAINING URINE.
Claim 2
Independent Claim 99 words
THE METHOD OF MAKING A LYOPHILIZED NORMAL HUMAN URINE DURG CONTROL FROM POOLED NORMAL HUMAN URINE FOR USE AS A CONTROL IN HUMAN URINE DRUG SCREENING AND ANALYSIS PROCEDURES WHICH COMPRISES: A. MIXING A WASHED STYRENE-DIVINYLBENZENE COPOLYMER RESIN AND HUMAN URINE TOGETHER IN THE RATIO OF ABOUT 5 GRAMS OF RESIN PER 100 ML. OF URINE FOR ABOUT ONE-HALF HOUR, B. SEPARATING THE RESIN TREATED URINE FROM SAID RESIN, C. FILTERING THE SEPARATED RESIN TREATED URINE THROUGH AN INFUSORIAL EARTH BED, D. ADDING KNOWN CONCENTRATIONS OF PURE DRUGS TO THE FILTERED URINE, AND E. LYOPHILIZING THE DRUG CONTAINING URINE.
Claim 3
Dependent Claim 13 words
The method of claim 1 wherein the styrene-divinylbenzene copolymer resin is Amberlite XAD-2.
Claim 4
Dependent Claim 12 words
The method of claim 1 wherein the infusorial earth bed is Celite.
Claim 5
Dependent Claim 28 words
A lyophilized pooled normal human urine drug control for use as a control in human urine drug screening and analysis procedures prepared by the method of claim 1.
Claim 6
Dependent Claim 18 words
The lyophilized pooled normal human urine drug control of claim 4, reconstituted by the addition of distilled water.
Claim 7
Dependent Claim 34 words
In the performance of human urine drug screening and analysis procedures, the improvement comprising employing in said procedures the reconstituted lyophilized pooled normal human urine drug control prepared by the method of claim 1.

References Cited (Backward Citations)

US3625652A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-08-25 1979-02-24 1979-08-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-08-25 1983-02-24 1983-08-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-08-25 1987-02-24 1987-08-26 $7700.00 Window Closed / Lapsed

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