Patent US3897453A successfully refreshed from Google Patents.
US3897453A
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Dibenzofuran and dibenzothiophene acetic acid derivatives
Assignee: Merck Patent GmbH
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Filing: 1973-05-10
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Granted: 1975-07-29
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Expires: 1993-05-10
Abstract
Abstract Dibenzofuran and dibenzothiophene derivatives of the formula WHEREIN R1 is COOH, CHO, or CH2OH, R2 is H or alkyl of 1-4 carbon atoms, R3 is H, alkyl, alkoxy, alkanoyl, monoalkylamino, dialkylamino, or acylamino of up to 4 carbon atoms, F, Cl, Br, I, OH, NH2, NO2, CN, or CF3; and Y is O or S, with the proviso that at least one of R2 and R3 is other than H, and the physiologically acceptable salts thereof, possess antiinflammatory activity.
Inventors
- 👤 Joachim Gante
- 👤 Werner Mehrhof
- 👤 Albrecht Wild
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 07:10
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/91; C07D333/00; C07D333/50; C07D333/76
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim
27 words
A compound of claim 1, wherein R1 is COOR6 in which R6 is H, alkyl of 1-8 carbon atoms or dialkylaminoalkyl of up to 10 carbon atoms.
Claim 4
Dependent Claim
12 words
A compound of claim 1, wherein R1 is COOH, COOCH3 or COOC2H5.
Claim 5
Dependent Claim
11 words
A compound of claim 1, wherein R2 is CH3 or C2H5.
Claim 6
Dependent Claim
9 words
A compound of claim 4, wherein R2 is CH3.
Claim 7
Dependent Claim
21 words
A compound of claim 1, wherein R3 is H, CH3, C2H5, CH3O, CH3CO, F, Cl, Br, I, OH, NH2 or NO2.
Claim 8
Dependent Claim
9 words
A compound of claim 6, wherein R3 is H.
Claim 9
Dependent Claim
31 words
A compound of claim 1, wherein R1 is COOH or COOAlkyl wherein alkyl is of 1-8 carbon atoms, R2 is CH3 and R3 is H, C2H5, F, Cl, Br or I.
Claim 10
Dependent Claim
11 words
A compound of claim 8, wherein R3 is H or F.
Claim 11
Dependent Claim
11 words
A compound of claim 8, wherein R3 is H or 7-F.
Claim 12
Dependent Claim
7 words
A compound of claim 1, 2-(2-dibenzofuryl)-propionic acid.
Claim 13
Dependent Claim
11 words
A compound of claim 1, the ethyl ester of 2-(2-dibenzofuryl)-propionic acid.
Claim 14
Dependent Claim
11 words
A compound of claim 1, the 2-diethylaminoethyl ester of 2-(2-dibenzofuryl)-propionic acid.
Claim 15
Dependent Claim
8 words
A compound of claim 1, the 2-(2-dibenzofuryl)-butyric acid.
Claim 16
Dependent Claim
8 words
A compound of claim 1, the 2-(2-dibenzothienyl)-propionic acid.
Claim 17
Dependent Claim
11 words
A compound of claim 1, the ethyl ester of 2-(2-dibenzothienyl)-propionic acid.
Claim 18
Dependent Claim
11 words
A compound of claim 1, the 2-diethylaminoethyl ester of 2-(2-dibenzothienyl)-propionic acid.
Claim 19
Dependent Claim
8 words
A compound of claim 1, the 2-(8-ethyl-2-dibenzofuryl)-propionic acid.
Claim 20
Dependent Claim
11 words
A compound of claim 1, the ethyl ester of 2-(8-ethyl-2-dibenzofuryl)-propionic acid.
Claim 21
Dependent Claim
8 words
A compound of claim 1, the 2-(7-fluoro-2-dibenzofuryl)-propionic acid.
Claim 22
Dependent Claim
11 words
A compound of claim 1, the ethyl ester of 2-(7-fluoro-2-dibenzofuryl)-propionic acid.
Claim 23
Dependent Claim
8 words
A compound of claim 1, the 2-(8-fluoro-2-dibenzofuryl)-propionic acid.
Claim 24
Dependent Claim
8 words
A compound of claim 1, the 2-(7-chloro-2-dibenzofuryl)-propionic acid.
Claim 25
Dependent Claim
8 words
A compound of claim 1, the 2-(8-bromo-2-dibenzofuryl)-propionic acid.
Claim 26
Dependent Claim
11 words
A compound of claim 1, the ethyl ester of 2-(8-bromo-2-dibenzofuryl)-propionic acid.
Claim 27
Dependent Claim
8 words
A compound of claim 1, the 2-(8-iodo-2-dibenzofuryl)-propionic acid.
Claim 28
Dependent Claim
11 words
A compound of claim 1, the 4-carbethoxycyclohexyl-ammonium salt of 2-(2-dibenzofuryl)-propionic acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-07-28 | 1979-01-27 | 1979-07-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-07-28 | 1983-01-27 | 1983-07-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-07-28 | 1987-01-27 | 1987-07-29 | $7700.00 | Window Closed / Lapsed |