Patent US3897412A successfully refreshed from Google Patents.
US3897412A
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Paromomycin antibiotic derivatives
Assignee: Bristol Myers Co
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Filing: 1973-06-15
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Granted: 1975-07-29
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Expires: 1993-06-15
Abstract
Abstract Derivatives of paromomycin have been prepared which possess substantially improved antibacterial activity. An example of such an agent is 1-(L-(-)- gamma -amino- Alpha hydroxybutyryl)paromomycin (IVa,BB-K47).
Inventors
- 👤 Takayuki Naito
- 👤 Susumu Nakagawa
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 23:07
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/22; C07H15/222; C07H15/226; C07H15/228; C07H15/232; C07C; C07C2603/00; C07C2603/02; C07C2603/04; C07C2603/22; C07C2603/26
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
5 words
A COMPOUND HAVING THE FORMULA
Claim 2
Dependent Claim
5 words
A COMPOUND HAVING THE FORMULA
Claim 3
Dependent Claim
8 words
The compound of claim 1 wherein R1 is
Claim 4
Dependent Claim
23 words
A compound of claim 1 wherein R1 is C6H5CH2-O-C- and R2 is L-(-)- Beta -benzyloxycarbonylamino- Alpha -hydroxypropionyl or L-(-)- delta -benzyloxycarbonylamino- Alpha -hydroxyvaleryl.
Claim 5
Dependent Claim
31 words
A compound of claim 1 wherein R1 is H and R2 is L-(-)- Beta -amino- Alpha -hyDroxypropionyl or L-(-)- delta -amino- Alpha -hydroxyvaleryl; or a nontoxic pharmaceutically acid addition salt thereof.
Claim 6
Dependent Claim
24 words
The compound of claim 4 wherein R1 is H and R2 is L-(-)- Beta -amino- Alpha -hydroxypropionyl; or the mono- or disulfate salt thereof.
Claim 7
Dependent Claim
21 words
The compound of claim 4 wherein R1 is H and R2 is L-(-)-delta -amino- Alpha -hydroxyvaleryl; or the monodisulfate salt thereof.
References Cited (Backward Citations)
US3781268A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-07-28 | 1979-01-27 | 1979-07-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-07-28 | 1983-01-27 | 1983-07-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-07-28 | 1987-01-27 | 1987-07-29 | $7700.00 | Window Closed / Lapsed |