Patent US3890439A successfully refreshed from Google Patents.
US3890439A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Imidazolidinone derivatives in the treatment of emesis and psychosomatic disturbances
Assignee: Novartis Corp
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Filing: 1973-10-12
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Granted: 1975-06-17
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Expires: 1993-10-12
Abstract
Abstract Compounds of the class of 1-(2-(4-(3-(p-fluoro-benzoyl)-alkyl)1-piperazinyl)-ethyl)-3-alkyl-2 -imidazolidinone which may be substituted in the 4-position of the imidazolidinone ring by an alkyl group having 1 to 4 carbon atoms and pharmaceutically acceptable acid addition salts thereof have an anti-emetic action and also a moderate central depressant action, e.g. they inhibit motility. They moreover exhibit no cataleptic inherent action. Such compounds can be prepared for instance by reaction of 1-(2(1-piperazinyl)-ethyl)-3-methyl-2-imidazolidinone with 4-chloro4''-fluorobutyrophenone. The compounds are active ingredients of pharmaceutical compositions.
Inventors
- 👤 Armin Zust
- 👤 Walter Schindler
- 👤 Executor By Leonhard Gysin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 07:40
CPC Classifications
C; C07; C07D; C07D403/00; C07D403/02; C07D403/06; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
26 words
A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF EMESIS OF VARYING ORIGIN AND OF PSYCHOSOMATIC DISTURBANCES COMPRISING A THERAPEUTICALLY EFFECTIVE AMOUNT OF A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim
26 words
A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF EMESIS OF VARYING ORIGIN AND OF PSYCHOSOMATIC DISTURBANCES COMPRISING A THERAPEUTICALLY EFFECTIVE AMOUNT OF A COMPOUND OF THE FORMULA
Claim 3
Independent Claim
33 words
A method for the treatment of emesis of varying origin and of psychosomatic disturbances which comprises administration to a warm blooded animal of a therapeutically effective amount of a compound of the formula
Claim 4
Independent Claim
33 words
A method for the treatment of emesis of varying origin and of psychosomatic disturbances which comprises administration to a warm blooded animal of a therapeutically effective amount of a compound of the formula
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-06-16 | 1978-12-16 | 1979-06-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-06-16 | 1982-12-16 | 1983-06-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-06-16 | 1986-12-16 | 1987-06-17 | $7700.00 | Window Closed / Lapsed |