Patent US3885439A successfully refreshed from Google Patents.
US3885439A
Expired / Lapsed
US
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Rotating sampling valve
Assignee: F Hoffmann La Roche AG
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Filing: 1973-10-24
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Granted: 1975-05-27
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Expires: 1993-10-24
Abstract
Abstract A rotating sampling valve is described consisting of a rotating plate held between two fixed plates. The rotating plate contains a plurality of channels bored through its longitudinal axis which channels are disposed symmetrically around its center axis. Both the upper and lower fixed plates contain the same number of correspondingly placed channels. Thus, when the center plate is rotated liquid flowing through the channels in the center plate are entrapped and transferred to a position indexing with different channels in the upper and lower plates. This sampling valve is useful in obtaining discontinuous samples from column eluents for analytical assay such as, for example, fluorescence analysis of proteins, peptides and amino acids, or in other chemical analysis, process control and other purposes.
Inventors
- 👤 James Edward Stone
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 08:48
CPC Classifications
G; G01; G01N; G01N35/00; G01N35/10; G01N35/1095; G01N35/1097; Y; Y10; Y10T; Y10T137/00; Y10T137/4238
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
280 words
A rotating sample valve comprising: a. a cylindrical plate containing a plurality of channels parallel to its longitudinal axis, said channels being symmetrically disposed about the center axis of said cylindrical plates; b. an upper and lower fixed plate between which said cylindrical plate is rotatably mounted, said upper plate and lower plate each containing the same plurality of channels symmetrically disposed around their respective center axis so that such channels are in operative flow relation with corresponding channels in said cylindrical plate; c. a stepping motor means which is operatively connected to said cylindrical plate, which stepping motor means has a step proportional to the number of channels in each said cylindrical, upper and lower plates; wherein one of said channels in said upper plate is operatively connected with inlet means for a first liquid stream and the corresponding channel in the lower plate is operatively connected to outlet means, wherein another of said channels in said upper plate is operatively connected with inlet means for a second liquid stream and the corresponding channel in the lower plate is operatively connected with a second outlet means; and wherein another of said channels in said upper plate is operatively connected with inlet means for a third liquid stream and the corresponding channel of said lower plate is operatively connected with a third outlet means, whereby a signal to said stepping motor means causes rotation of said cylindrical plate relative to said upper and lower plates with concomitant entrapment of any liquid stream contained in said channels in said cylindrical plate and transport of said entrapped stream to the next position of said cylindrical plate with respect to said fixed plates.
Claim 2
Dependent Claim
280 words
A rotating sample valve comprising: a. a cylindrical plate containing a plurality of channels parallel to its longitudinal axis, said channels being symmetrically disposed about the center axis of said cylindrical plates; b. an upper and lower fixed plate between which said cylindrical plate is rotatably mounted, said upper plate and lower plate each containing the same plurality of channels symmetrically disposed around their respective center axis so that such channels are in operative flow relation with corresponding channels in said cylindrical plate; c. a stepping motor means which is operatively connected to said cylindrical plate, which stepping motor means has a step proportional to the number of channels in each said cylindrical, upper and lower plates; wherein one of said channels in said upper plate is operatively connected with inlet means for a first liquid stream and the corresponding channel in the lower plate is operatively connected to outlet means, wherein another of said channels in said upper plate is operatively connected with inlet means for a second liquid stream and the corresponding channel in the lower plate is operatively connected with a second outlet means; and wherein another of said channels in said upper plate is operatively connected with inlet means for a third liquid stream and the corresponding channel of said lower plate is operatively connected with a third outlet means, whereby a signal to said stepping motor means causes rotation of said cylindrical plate relative to said upper and lower plates with concomitant entrapment of any liquid stream contained in said channels in said cylindrical plate and transport of said entrapped stream to the next position of said cylindrical plate with respect to said fixed plates.
Claim 3
Dependent Claim
14 words
The valve of claim 1 wherein said stepping motor means is a stepping motor.
Claim 4
Dependent Claim
25 words
The valve of claim 2 wherein said stepping motor steps 120* and there are three channels In each of said cylindrical, upper and lower plates.
Claim 5
Dependent Claim
43 words
The valve of claim 1 wherein the fixed plates are clamped together and the surface between the first plates and the cylindrical plate are machined to a low friction finish so that a liquid-tight seal is obtained between the aforesaid channels and plates.
Claim 6
Dependent Claim
62 words
The valve of claim 1 wherein said plurality of channels in each of said cylindrical, upper and lower plates consists of a number which is a multiple of three wherein in each continguous triad of channels in said fixed upper plate there is a sample liquid stream inlet means, a buffer solution inlet means and a water wash stream inlet means, respectively.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-05-26 | 1978-11-25 | 1979-05-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-05-26 | 1982-11-25 | 1983-05-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-05-26 | 1986-11-25 | 1987-05-27 | $7700.00 | Window Closed / Lapsed |