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Tablet formulation

Assignee: Ives Lab
•
Filing: 1972-12-06
•
Granted: 1975-05-13
•
Expires: 1992-12-06
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Abstract

Abstract The disclosure is directed to formulations for tablets which are to be deeply grooved to facilitate breaking into predetermined portions by the user. A critical tablet weight for deeply grooved tablets is disclosed.

Inventors

  • 👤 Ehud Geller

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 20:56
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2072; A61J; A61J3/00; A61J3/10

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 87 words
A PHARMACEUTICAL TABLET WHICH IS ADEQUATELY IMPRINTED WITH INDICIA OR EMBOSING AND SCORED TO FORM A GROOVE WHICH IS ONE-THIRD TO TWO-THIRDS THE DEPTH OF THE TOTAL TABLET THICKNES TO FACTILITATE SEPARATION INTO SUBDIVISIONS CONTAINING SUBSTANTIALLY EQUAL AMOUNTS OF A PHARMACEUTICALLY ACTIVE INGREDIENT COMPRISING A DIRECTLY COMPRESSED FORMULATION OF 5 TO 10 MILLIGRAMS OF AN ACTIVE INGREDIENT, THE REMAINDER BEING 45 TO 99.7 PERCENT BY WEIGHT OF MICROCRYSTALLINE CELLULOSE AND 0.3 TO 0.4 PERCENT BY WEIGHT OF MAGNESIUM STEARATE, ALONG WITH FILLERS, EXTENDERS, FLAVORING AND THE LIKE.
Claim 2
Dependent Claim 87 words
A PHARMACEUTICAL TABLET WHICH IS ADEQUATELY IMPRINTED WITH INDICIA OR EMBOSING AND SCORED TO FORM A GROOVE WHICH IS ONE-THIRD TO TWO-THIRDS THE DEPTH OF THE TOTAL TABLET THICKNES TO FACTILITATE SEPARATION INTO SUBDIVISIONS CONTAINING SUBSTANTIALLY EQUAL AMOUNTS OF A PHARMACEUTICALLY ACTIVE INGREDIENT COMPRISING A DIRECTLY COMPRESSED FORMULATION OF 5 TO 10 MILLIGRAMS OF AN ACTIVE INGREDIENT, THE REMAINDER BEING 45 TO 99.7 PERCENT BY WEIGHT OF MICROCRYSTALLINE CELLULOSE AND 0.3 TO 0.4 PERCENT BY WEIGHT OF MAGNESIUM STEARATE, ALONG WITH FILLERS, EXTENDERS, FLAVORING AND THE LIKE.
Claim 3
Dependent Claim 18 words
The tablet as defined in claim 1 in which the total tablet weight is 150 to 175 milligrams.
Claim 4
Dependent Claim 17 words
A tablet as defined in claim 1 in which the total tablet weight is about 175 milligrams.
Claim 5
Dependent Claim 36 words
A tablet as defined in claim 1 in which the microcrystalline cellulose is present in the amount of 60 percent by weight and the magnesium stearate is present in the amount of 0.35 percent by weight.
Claim 6
Dependent Claim 20 words
A tablet as defined in claim 1 in which the active ingredient is 5 to 10 milligrams of isosorbide dinitrate.

References Cited (Backward Citations)

US1836604A Cited
US3146168A Cited
US3336200A Cited
US3723614A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-05-12 1978-11-11 1979-05-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-05-12 1982-11-11 1983-05-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-05-12 1986-11-11 1987-05-13 $7700.00 Window Closed / Lapsed

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