Patent US3883498A successfully refreshed from Google Patents.
US3883498A
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{8 Ile{hu 3{b , Leu{hu 4{b {9 -vasopressin analogs
Assignee: F Hoffmann La Roche AG
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Filing: 1973-09-07
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Granted: 1975-05-13
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Expires: 1993-09-07
Abstract
Abstract Analogs of the hormone vasopressin are described. These new hormones, X-(Ile3,Leu4)-argininevasopressin and X-(Ile3,Leu4)lysinevasopressin exhibit particularly strong natriuretic activity.
Inventors
- 👤 Dieter Gillessen
- 👤 Josef Rudinger
- 👤 Rolf Studer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 14:50
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/575; A; A61; A61K; A61K38/00; A61K38/04; A61K38/08; A61K38/095; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/15
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
6 words
A COMPOUND OF THE GENERAL FORMULA
Claim 2
Dependent Claim
6 words
A COMPOUND OF THE GENERAL FORMULA
Claim 3
Dependent Claim
8 words
A compound of claim 1 of the formula
Claim 4
Dependent Claim
16 words
A compound of claim 2 wherein X is the residue of a naturally occurring amino acid
Claim 5
Dependent Claim
9 words
The compound of claim 3 which is Gly-(Ile3,Leu4)-argininevasopressin diacetate.
Claim 6
Dependent Claim
20 words
A compound of claim 1 wherein X is a linear peptide of 2-6 amino acids selected from leucine and glycine.
Claim 7
Dependent Claim
9 words
The compound of claim 5 which is Leu-Gly-Gly-(Ile3,Leu4)-lysinevasopressin triacetate.
Claim 8
Dependent Claim
8 words
A compound of claim 1 of the formula
Claim 9
Dependent Claim
16 words
A compound of claim 7 wherein X is the residue of a naturally occurring amino acid.
Claim 10
Dependent Claim
9 words
The compound of claim 8 which is Pro-(Ile3,Leu4)-lysinevasopressin diacetate.
Claim 11
Dependent Claim
9 words
A compound of claim 8 which is Lys-(Ile3,Leu4)-lysinevasopressin diacetate.
Claim 12
Dependent Claim
9 words
The compound of claim 8 which is Glu-(Ile3,Leu4)-lysinevasopressin acetate.
Claim 13
Dependent Claim
20 words
A compound of claim 7 wherein X is a linear peptide of 2-6 amino acids selected from leucine and glycine.
Claim 14
Dependent Claim
9 words
The compound of claim 12 which is Leu-Gly-(Ile3,Leu4)-lysinevasopressin diacetate.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-05-12 | 1978-11-11 | 1979-05-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-05-12 | 1982-11-11 | 1983-05-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-05-12 | 1986-11-11 | 1987-05-13 | $7700.00 | Window Closed / Lapsed |