Patent US3879544A successfully refreshed from Google Patents.
US3879544A
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US
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Method for suppressing histamine release
Assignee: Meda Pharmaceuticals Inc
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Filing: 1973-05-09
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Granted: 1975-04-22
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Expires: 1993-05-09
Abstract
Abstract WHEREIN X is halogen or lower alkyl; m is an integer 1 or 2 and n is an integer from 2 to 6 inclusive, in sufficient amount to suppress the release of histamine from said cells. A method for suppressing the release of histamine from sensitized leukocytes which comprises administering arylthioalkanols of the formula:
Inventors
- 👤 David B Reisner
- 👤 Bernard J Ludwig
- 👤 George M Fukui
- 👤 Frank M Berger
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 07:38
CPC Classifications
C; C07; C07C; C07C321/00; C07C323/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
52 words
A METHOD FOR SUPPRESSING THE RELEASE OF HISTAMINE FROM SENSITIZED LEUKOCYTES IN A WARM BLOODED ANIMAL IN NEED OF SUCH TREATMENT WHICH COMPRISES ADMINISTERING INTERNALLY TO SAID ANIMAL, IN AN AMOUNT SUFFICIENT TO SUPPRESS THE RELEASE OF HISTAMINE IN SAID ANIMAL, A COMPOUND SELECTED FROM THE GROUP OF COMPOUNDS HAVING THE FORMULA:
Claim 2
Independent Claim
52 words
A METHOD FOR SUPPRESSING THE RELEASE OF HISTAMINE FROM SENSITIZED LEUKOCYTES IN A WARM BLOODED ANIMAL IN NEED OF SUCH TREATMENT WHICH COMPRISES ADMINISTERING INTERNALLY TO SAID ANIMAL, IN AN AMOUNT SUFFICIENT TO SUPPRESS THE RELEASE OF HISTAMINE IN SAID ANIMAL, A COMPOUND SELECTED FROM THE GROUP OF COMPOUNDS HAVING THE FORMULA:
Claim 3
Independent Claim
52 words
A method for suppressing the release of histamine from sensitized leukocytes in a warm blooded animal in need of such treatment which comprises administering internally to said animal, in an amount sufficient to suppress the release of histamine in said animal, a compound selected from the group of compounds having the formula:
Claim 4
Independent Claim
52 words
A method for suppressing the release of histamine from sensitized leukocytes in a warm blooded animal in need of such treatment which comprises administering internally to said animal, in an amount sufficient to suppress the release of histamine in said animal, a compound selected from the group of compounds having the formula:
Claim 5
Dependent Claim
27 words
The method of claim 1 wherein X is lower alkyl; m is an integer 1 or 2 and n is an integer from 2 to 6, inclusive.
Claim 6
Dependent Claim
24 words
The method of claim 1 wherein X is chlorine; m is an integer 1 and n is an integer from 2 to 6, inclusive.
Claim 7
Dependent Claim
10 words
The method of claim 1 wherein the compound is 4-(p-tolylthio)butanol.
Claim 8
Dependent Claim
10 words
The method of claim 1 wherein the compound is 4-(p-chlorophenylthio)butanol.
Claim 9
Dependent Claim
10 words
The method of claim 1 wherein the compound is 1-(p-chlorophenylthio)-2-butanol.
Claim 10
Dependent Claim
10 words
The method of claim 1 wherein the compound is 3-(p-chlorophenylthio)-2-methylpropanol.
Claim 11
Dependent Claim
10 words
The method of claim 1 wherein the compound is 5-(p-chlorophenylthio)-2-pentanol.
Claim 12
Dependent Claim
10 words
The method of claim 1 wherein the compound is 4-(o-chlorophenylthio)butanol.
Claim 13
Dependent Claim
10 words
The method of claim 1 wherein the compound is 5-(p-chlorophenylthio)-2-methyl-2-pentanol.
References Cited (Backward Citations)
US3048577A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-04-21 | 1978-10-21 | 1979-04-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-04-21 | 1982-10-21 | 1983-04-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-04-21 | 1986-10-21 | 1987-04-22 | $7700.00 | Window Closed / Lapsed |