N,n-bis-(diphenylalkyl)-alkylendiamine and their salts

Abstract

Abstract Group, wherein R.sub.5 and R.sub.6 are equal or different, representing alkyl radicals having one to three carbon atoms, or where one of the symbols R.sub.1, R.sub.2, R.sub.3 or R.sub.4 can represent a cycloaliphatic residue having five to seven carbon atoms, where A.sub.1 and A.sub.2 can be equal or different, representing unbranched or branched alkylene chains having one to four carbon atoms, or represent a direct link, and where B is an unbranched or branched alkylene chain having two to four carbon atoms, whereby in the event that B is a chain having 3 carbon atoms, one hydrogen atom belonging to the middle CH.sub.2 -group, can, if necessary, be replaced by an OH-group, and their obvious physiologically compatible acid addition salts having the same activity, which are characterized by exhibiting a strong coronary vasodilator effect. Wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are unsubstituted phenyl radicals, whereby one of these phenyl radicals or two of the phenyl radicals positioned on the opposite ends of the structure, can be singly or doubly substituted by alkyl- or alkoxy groups having one to three carbon atoms, by hydroxyl groups or by halogen atoms or once by a N,N''-bis-(diphenylalkyl)-alkylenediamines of the general structure

Inventors

• 👤 Rudolf Theodor Petersen
• 👤 Hans Friedrich Benthe

Bibliographic Details