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US3875014A Expired / Lapsed US ⏱️ 0.0 years remaining

Glutamic oxaloacetic transaminase test material

Assignee: IL Holding Spa
•
Filing: 1973-12-14
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Granted: 1975-04-01
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Expires: 1993-12-14
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Abstract

Abstract A diagnostic test indicator for the detection and determination of the concentration of glutamic oxaloacetic transaminase in sera comprising a pair of bibulous materials, the first one of which has contained therein the dried residue resulting from the impregnation thereof with 1. L-aspartic acid and 2. Alpha -KETOGLUTARIC ACID AND THE SECOND OF WHICH HAS CONTAINED THEREIN THE DRIED RESIDUE RESULTING FROM THE IMPREGNATION THEREOF WITH 3. A DIAZONIUM SALT, AND A PROCESS FOR THE PRODUCTION OF SAID INDICATOR, ARE DISCLOSED.

Inventors

  • 👤 Peter Salvatore Forgione

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 22:24
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/48; C12Q1/52; Y; Y10; Y10S; Y10S435/00; Y10S435/805

Claims Analysis

Total Claims: 23
Claim 1
Independent Claim 46 words
A DIAGNOSTIC TEST FOR THE DETECTION AND CONCENTRATION DETERMINATION OF GLUTAMIC OXALOACETRIC TRANSAMINASE IN SERA COMPRISING A PAIR OF BIBULOUS MATERIALS THE FIRST OF WHICH CONTAINS THEREIN, AT A PH OF FROM ABOUT 6.5 TO ABOUT 9.5, THE DRIED RESIDUE RESULTING FROM THE IMPREGNATION THEREOF WITH
Claim 2
Dependent Claim 46 words
A DIAGNOSTIC TEST FOR THE DETECTION AND CONCENTRATION DETERMINATION OF GLUTAMIC OXALOACETRIC TRANSAMINASE IN SERA COMPRISING A PAIR OF BIBULOUS MATERIALS THE FIRST OF WHICH CONTAINS THEREIN, AT A PH OF FROM ABOUT 6.5 TO ABOUT 9.5, THE DRIED RESIDUE RESULTING FROM THE IMPREGNATION THEREOF WITH
Claim 3
Dependent Claim 3 words
L-ASPARTIC ACID AND
Claim 4
Dependent Claim 3 words
L-ASPARTIC ACID AND
Claim 5
Dependent Claim 28 words
A-KETOGLUTARIC ACID AND THE SECOND OF WHICH CONTAINS THEREIN, AT A PH OF FROM ABOUT 2.5 TO ABOUT 4.5, THE DRIED RESIDUE RESULTING FROM THE IMPREGNATION THEREOF WITH
Claim 6
Dependent Claim 28 words
A-KETOGLUTARIC ACID AND THE SECOND OF WHICH CONTAINS THEREIN, AT A PH OF FROM ABOUT 2.5 TO ABOUT 4.5, THE DRIED RESIDUE RESULTING FROM THE IMPREGNATION THEREOF WITH
Claim 7
Dependent Claim 29 words
Alpha -ketoglutaric acid and the second of which contains therein, at a pH of from about 2.5 to about 4.5, the dried residue resulting from the impregnation thereof with
Claim 8
Dependent Claim 29 words
Alpha -ketoglutaric acid and the second of which contains therein, at a pH of from about 2.5 to about 4.5, the dried residue resulting from the impregnation thereof with
Claim 9
Dependent Claim 16 words
A diagnostic test indicator according to claim 1 wherein said (3) is a 2-methoxy-4-benzamido-5-methyl diazonium salt.
Claim 10
Dependent Claim 17 words
A diagnostic test indicator according to claim 1 wherein said first bibulous material also contains a buffer.
Claim 11
Dependent Claim 36 words
a diazonium salt, said bibulous materials being positioned in superimposed relationship and adhered to one another with a cellulose acetate adhesive, said adhesive covering the entire adhering surface of either or both of the bibulous materials.
Claim 12
Dependent Claim 36 words
a diazonium salt, said bibulous materials being positioned in superimposed relationship and adhered to one another with a cellulose acetate adhesive, said adhesive covering the entire adhering surface of either or both of the bibulous materials.
Claim 13
Dependent Claim 36 words
A DIAZONIUM SALT, SAID BIBULOUS MATERIALS BEING POSITIONED IN SUPERIMPOSED RELATIONSHIP AND ADHERED TO ONE ANOTHER WITH A CELLULOSE ACETATE ADHESIVE, SAID ADHESIVE COVERING THE ENTIRE ADHERING SURFACE OF EITHER OR BOTH OF THE BIBULOUS MATERIALS.
Claim 14
Dependent Claim 36 words
A DIAZONIUM SALT, SAID BIBULOUS MATERIALS BEING POSITIONED IN SUPERIMPOSED RELATIONSHIP AND ADHERED TO ONE ANOTHER WITH A CELLULOSE ACETATE ADHESIVE, SAID ADHESIVE COVERING THE ENTIRE ADHERING SURFACE OF EITHER OR BOTH OF THE BIBULOUS MATERIALS.
Claim 15
Dependent Claim 21 words
A diagnostic test indicator according to claim 1 wherein said second bibulous material also contains starch, urea or a mixture thereof.
Claim 16
Dependent Claim 15 words
A diagnostic test indicator according to claim 3 wherein said buffer is a phosphate buffer.
Claim 17
Dependent Claim 14 words
A diagnostic test indicator according to claim 1 wherein said bibulous materials are paper.
Claim 18
Dependent Claim 124 words
A process for the preparation of the diagnostic test indicator of claim 1 which comprises (A) impregnating a first bibulous material with an aqueous solution of said (1) and (2), (B) thereafter drying the thus impregnated first material, (C) impregnating a second bibulous material with an aqueous solution of said (3), (D) thereafter drying the thus impregnated second material, (E) coating the entire surface of one side of at least one of said bibulous materials with a solution of cellulose acetate adhesive, (F) thereafter drying all of the resultant coated surfaces, (G) applying a second coating of a solution of cellulose acetate adhesive to all of the resultant, dried coated surfaces, and (H) combining the thus coated first and second materials in superimposed relationship.
Claim 19
Dependent Claim 14 words
A process according to claim 7 wherein said (3) is a 2-methoxy-4-benzamido-5-methyl diazonium salt.
Claim 20
Dependent Claim 25 words
A process according to claim 7 wherein said solution of (1) and (2) is buffered to a pH of from about 7.5 to about 10.0.
Claim 21
Dependent Claim 13 words
A process according to claim 9 wherein said buffer is a phosphate buffer.
Claim 22
Dependent Claim 18 words
A process according to claim 7 wherein said solution of (3) contains starch, urea or a mixture thereof.
Claim 23
Dependent Claim 12 words
A process according to claim 7 wherein said bibulous materials are paper.

References Cited (Backward Citations)

US2999052A Cited
US3069330A Cited
US3694163A Cited
US3672845A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-03-31 1978-09-30 1979-04-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-03-31 1982-09-30 1983-04-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-03-31 1986-09-30 1987-04-01 $7700.00 Window Closed / Lapsed

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