Treatment of titanium tetrachloride dryer residue

Claim 1

CALCINED NODULAR TITANIUM TETRACHLORIDE DRYER RESIDUE COMPRISING METAL VALUES INCLUDING TITANIUM, IRON, VANADIUM TION OF A PREDETERMINED DOSAGE REGIMEN OF OPHTHALMIC DRUG TO THE EYE OF A MAMMALIAN PATIENT COMPRISING (1) AN INNER RESERAND CHROMIUM, SAID METAL VALUES BEING PRESENT SUBSTANTIALLY AS METAL OXIDES, SAID RESIDUE HAVING BEEN OBTAINED FROM PURIFYVOIR COMPRISES D OF A BIODEGRADABLE MATERIAL CONTAINING A DRUG FORMULATION FOR THE EYE CONFINED THEREIN AND PERMEABLE TO THE ING TITANIUM TETRACHLORIDE PRODUCED FROM TITANIUM-BEARING MATERIAL CONTAINING SUCH METAL VALUES, AND SAID NODULAR RESIPASSAGE OF DRUG, AND (2) AN OUTER MEMBRANE SURROUNDING THE INNER RESERVOIR, THE MEMBRANE PERMEABLE TO THE PASSAGE OF DUE HAVING BEEN CALCINED AT TEMPERATURES IN EXCESS OF 1000*F. DRUG, BUT AT A LOWER RATE THAN THROUGH THE INNER RESERVOIR, THE MEMBRANE FORMED FROM DRUG RELEASE RATE CONTROLLING BIOERODIBLE MATERIAL COMPRISING A POLYVALENT ION CROSS-LINKED ANIONIC POLYELECTRLYTE WITH THE POLYVALENT ION A MEMBER SELECTED FROM THE GROUP CONSISTING OF ALUMINUM, BARIUM, CADMIUM, CALCIUM, COPPER, IRON AND ZINC AND THE ANIONIC POLYELECTROLYTE, A MEMBER SELECTED FROM THE GROUP CONSISTING OF PHARMACEUTICALLY ACCEPTABLE AGAR, ALGIN, ALGINIC ACID, CARRAGEENAN, CELLULOSE, GUM ARABIC, GUM GHATTI, PECTIC ACID, PECTIN, PECTINIC ACID, AND POLYSACCHARIDE, WITH THE POLYELECTROLYTE CROSS-PECTINIC FROM TWO-TENTH TO THREE EQUIVALENTS CROSS-LINKING AGENT SELECTED SOLELY FROM SAID POLYVALENT CATION FOR EACH EQUIVALENT OF POLYELECTROLYTE, WHICH MATERIAL BIOLOGICAL ENVIRONMENT THEREIN PATIENT IN FORM FOUR HOURS TO THIRTY DAYS INTO INNOCUOUS PRODUCTS IN RESPONSE TO TE BIOLOGICAL ENVIRONMENT THEREIN BY A PROCESS OF POLYVALENT ION DISPLACEMENT WITH NONCROSS-LINKING IONS PRESENT IN THE EYE WITH SAID DISPLACEMENT RATE CORRESPONDING TO THE EXTENT OF POLYYVALENT ION CROSS-LINKED, AND WHEREIN THE MEMBRANE MATERIAL CONTINUOUSLY METERS THE FLOW OF A THERAPEUTICALLY EFFECTIVE AMOUNT OF SAID DRUG FROM THE RESERVOIR TO THE EYE OF THE PATENT AT A CONTROLLED RATE OVER A PROLONGED PERIOD OF TIME.