US3865832A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Substituted, 6,7 ethylenedioxy 4 hydroxy 3 non oxo carbonylic quinolines
Assignee: US Philips Corp
•
Filing: 1973-02-05
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Granted: 1975-02-11
•
Expires: 1993-02-05
Abstract
Abstract Compounds of the formula 1 have potent diuretic and saluretic effects and a very low toxicity. The compounds can be synthesized by usual methods and be given suitable forms for administration and be used for the treatment of inter alia edemas. The compounds are novel.
Inventors
- 👤 Theodorus Antonius Co Boschman
- 👤 Jacob Gerard Korsloot
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 11:11
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61P; A61P7/00; A61P7/10; C; C07; C07D; C07D215/00; C07D215/02; C07D215/16; C07D215/48; C07D215/54; C07D215/56; C07D319/00; C07D319/10; C07D319/14; C07D319/16; C07D319/20
Claims Analysis
Total Claims: 36
Claim 1
Independent Claim
12 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF QUINOLINES OF THE FORMULA
Claim 2
Dependent Claim
12 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF QUINOLINES OF THE FORMULA
Claim 3
Dependent Claim
14 words
Quinoline derivatives as claimed in claim 1, in which R3 represents a halogen atom.
Claim 4
Dependent Claim
19 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino ( 2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof formed with pharmaceutically acceptable acids of claim 1.
Claim 5
Dependent Claim
19 words
The 3-(methoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino ( 2,3-g)) quinoline-8-carboxylic acid ethyl ester and salts thereof formed with pharmaceutically acceptable acids of claim 1.
Claim 6
Dependent Claim
19 words
The 3-(ethoxymethyl)-10-chloro-2,3-dihydro-9-hydroxy-p-dioxino ( 2,3-g)) quinoline-8-carboxylic acid ethyl ester and salts therefore formed with pharmaceutically acceptable acids of claim 1.
Claim 7
Dependent Claim
20 words
The 3-(n-propoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino ( 2, 3-g)) quinoline-8-carboxylic acid ethyl ester and salts thereof formed with pharmaceutically acceptable acids of claim 1.
Claim 8
Dependent Claim
18 words
The 3-(n.butoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof formed with pharmaceutically acceptable acids of claim 1.
Claim 9
Dependent Claim
18 words
The 3-(isobutoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof formed with pharmaceutically acceptable acids of claim 1.
Claim 10
Dependent Claim
18 words
The 3-(allyloxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof formed with pharmaceutically acceptable acids of claim 1.
Claim 11
Dependent Claim
18 words
The 3-(cyclopentyloxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino 2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof formed with pharmaceutically acceptable acids of claim 1.
Claim 12
Dependent Claim
18 words
The 3-(benzyloxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2, 3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 13
Dependent Claim
16 words
The 3-((2-methoxyethoxy)-methyl)-2,3-dihydro-9-hydroxy-p-dioxino(2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 14
Dependent Claim
18 words
The 3-(methylthiomethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2, 3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 15
Dependent Claim
18 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid, alkali metal salts and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 16
Dependent Claim
17 words
The 3-(hydroxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 17
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid n.propyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 18
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-methoxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid methyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 19
Dependent Claim
18 words
The 9,10-dichloro-3-(ethoxymethyl)-2,3-dihydro-p-dioxino (2, 3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 20
Dependent Claim
17 words
The 10-chloro-3-(ethoxymethyl)-2,3-dihydro-9-methoxy-p-dioxino (2,3-g) quinoliNe-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 21
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-mercapto-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 22
Dependent Claim
16 words
The 10-chloro-3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g)quinoline-8-carboxylic acid allyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 23
Dependent Claim
17 words
The 10-chloro-3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid (2-ethoxymethyl) ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 24
Dependent Claim
17 words
The 10-chloro-3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid cyclopentyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 25
Dependent Claim
17 words
The 10-chloro-3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid (cyclopropylmethyl) ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 26
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-10-nitro-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 27
Dependent Claim
17 words
The 10-amino-3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 28
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-10-(tri-fluoromethyl)-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 29
Dependent Claim
18 words
The 3-(hydroxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid, alkali metal salts and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 30
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-10-chloro-p-dioxino (2,3-g) quinoline-8-carboxylic acid, alkali metal salts and salts thereof with pharmaceutically acceptable acids of claim
Claim 31
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 32
Dependent Claim
17 words
The 3-(acetoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 33
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-10-methyl-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 34
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-10-methoxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid ethyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 35
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxylic acid methyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
Claim 36
Dependent Claim
17 words
The 3-(ethoxymethyl)-2,3-dihydro-9-hydroxy-p-dioxino (2,3-g) quinoline-8-carboxyl acid isobutyl ester and salts thereof with pharmaceutically acceptable acids of claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-02-10 | 1978-08-12 | 1979-02-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-02-10 | 1982-08-12 | 1983-02-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-02-10 | 1986-08-12 | 1987-02-11 | $7700.00 | Window Closed / Lapsed |