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US3864360A Expired / Lapsed US ⏱️ 0.0 years remaining

N-(2-{8 3-hydroxy-3-phenyl-2-phthalimidinyl{9 -ethyl)-sulfonamides

Assignee: Wyeth LLC
•
Filing: 1972-08-14
•
Granted: 1975-02-04
•
Expires: 1992-08-14
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Abstract

Abstract Novel compounds have been prepared which have useful pharmacological activity as well as intermediates for their production. Some of the processes have utility for the production of other pharmacologically active compounds. The active compounds of this invention are those of the following formulas: WHEREIN R1 is selected from the group consisting of phenyl, monohalophenyl, dihalophenyl, mono(lower)alkylphenyl, di(lower)alkylphenyl, trifluoromethylphenyl, mono(lower)alkoxyphenyl, di(lower)alkoxyphenyl, thienyl, pyridyl, furyl, and tetrahydro-2-naphthyl; R2 is selected from the group consisting of hydrogen, halogen, amino, (lower)alkylamino, (lower)alkyl and (lower) alkoxy; R3 is hydrogen when R2 and R3 are dissimilar and when R2 and R3 are the same they are both selected from the group consisting of hydrogen, halogen, (lower)alkyl and (lower)alkoxy; R4 and R5 are lower alkyl and attached to the same carbon atom; X is the anion portion of a pharmacologically acceptable acid-addition salt.

Inventors

  • 👤 Theodore S Sulkowski
  • 👤 Albert A Mascitti

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 06:21
CPC Classifications
C; C07; C07D; C07D233/00; C07D233/04; C07D233/20; C07D233/22; C07D209/00; C07D209/02; C07D209/44; C07D209/48

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 12 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF THOSE HAVING THE FORMULA:
Claim 2
Dependent Claim 12 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF THOSE HAVING THE FORMULA:
Claim 3
Dependent Claim 11 words
A compound as described in claim 1 which is: N-(2-(3-(p-chlorophenyl)-3-hydroxy-2-phthalimidinyl)-1,1-dimethylethyl)-p -toluenesulfonamide.
Claim 4
Dependent Claim 11 words
A compound as described in claim 1 which is: N-(2-(3-(p-fluorophenyl)-3-hydroxy-2-phthalimidinyl)-1,1-dimethylethyl)-p -toluenesulfonamide.
Claim 5
Dependent Claim 11 words
A compound as described in claim 1 which is: N-(2-(3-hydroxy-3-phenyl-2-phthalimidinyl)-1,1-dimethylethyl)-p -toluenesulfonamide.
Claim 6
Dependent Claim 11 words
A compound as described in claim 1 which is: N-(2-(3-(p-bromophenyl)-3-hydroxy-2-phthalimidinyl)-1,1-dimethylethyl)-p -toluenesulfonamide.
Claim 7
Dependent Claim 11 words
A compound as described in claim 1 which is: N-(2-(3-(p-chlorophenyl)-3-hydroxy-2-phthalimidinyl)ethyl)-p -toluenesulfonamide.
Claim 8
Dependent Claim 10 words
A compound as described in claim 1 which is: N-(2-(3-hydroxy-3-phenyl-2-phthalimidinyl)ethyl)-p-toluenesulfonamide.

References Cited (Backward Citations)

US3634452A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-02-03 1978-08-05 1979-02-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-02-03 1982-08-05 1983-02-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-02-03 1986-08-05 1987-02-04 $7700.00 Window Closed / Lapsed

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