US3862162A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Certain-2-amino-1,4-dihydro-4-phenyl-6-lower alkyl (or phenyl)-3-pyridinecarboxylates
Assignee: Bayer AG
•
Filing: 1973-08-21
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Granted: 1975-01-21
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Expires: 1993-08-21
Abstract
Abstract 2-Amino-1,4 dihydropyridines bearing an ester carbonyl function in the 3-position, being optionally substituted by lower alkyl in the 5-position, and being substituted in the 4- and 6-positions by lower alkyl, phenyl, substituted phenyl or a heterocyclic group are antihypertensive agents and coronary vessel dilators. The compounds, of which 2-amino-6-methyl-4-(3-chlorophenyl)-1,4dihydropyridine-3 carboxylic acid ethyl ester is a representative embodiment, are prepared through condensation of an Alpha - Beta -unsaturated ketone and an amidine.
Inventors
- 👤 Horst Meyer
- 👤 Friedrich Bossert
- 👤 Wulf Vater
- 👤 Kurt Stoepel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 10:31
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/80; C07D211/84; C07D211/90
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
5 words
A compound of the formula:
Claim 2
Dependent Claim
5 words
A compound of the formula:
Claim 3
Dependent Claim
12 words
The compound according to claim 1 which is 2-amino-4,6-diphenyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester.
Claim 4
Dependent Claim
12 words
The compound according to claim 1 which is 2-amino-6-methyl-4-(2-chlorophenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester.
Claim 5
Dependent Claim
12 words
The compound accOrding to claim 1 which is 2-amino-6-methyl-4-(4-methoxyphenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester.
Claim 6
Dependent Claim
12 words
The compound according to claim 1 which is 2-amino-6-methyl-4-(3-chlorophenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester.
Claim 7
Dependent Claim
12 words
The compound according to claim 1 which is 2-amino-6-phenyl-4-(3-chlorophenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester.
Claim 8
Dependent Claim
12 words
The compound according to claim 1 which is 2-amino-6-phenyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester.
Claim 9
Dependent Claim
12 words
The compound according to claim 1 which is 2-amino-6-methyl-4-(2-methylphenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester.
Claim 10
Dependent Claim
12 words
The compound according to claim 1 which is 2-amino-6-phenyl-4-(2-chlorophenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester.
Claim 11
Dependent Claim
12 words
The compound according to claim 1 which is 2-amino-6-methyl-4-(2-chlorophenyl)-1,4-dihydropyridine-3-carboxylic acid isopropyl ester.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-20 | 1978-07-22 | 1979-01-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-20 | 1982-07-22 | 1983-01-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-20 | 1986-07-22 | 1987-01-21 | $7700.00 | Window Closed / Lapsed |