Abstract This invention is concerned with novel and pharmaceutically active indole derivatives having the structure: AND THE SALTS THEREOF WITH PHYSIOLOGICALLY ACCEPTABLE ACIDS, IN WHICH EACH OF X and Y is selected from the group consisting of hydrogen, hydroxy, lower alkyl having 1-3 carbon atoms and lower alkoxy having 1-3 carbon atoms, R1 is selected from the group consisting of hydrogen, lower alkyl having 1-4 carbon atoms and benzyl, R2 is selected from the group consisting of hydrogen, lower alkyl having 1-4 carbon atoms, benzyl and phenyl, R3 is selected from the group consisting of hydrogen, lower alkyl having 1-8 carbon atoms, cycloalkyl having 5 or 6 carbon atoms, benzyl and 2-phenylethyl, and A is a straight or branched alkylene chain containing from 2 to 4 carbon atoms.