Patent US1966316A successfully refreshed from Google Patents.
Patent US3859437A successfully refreshed from Google Patents.
US3859437A
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Reducing cholesterol levels
Assignee: CHOLEX LABORATORIES INC A CORP OF NY
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Filing: 1973-04-02
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Granted: 1975-01-07
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Expires: 1993-04-02
Abstract
Abstract A method for reducing the levels of cholesterol and other lipids in mammals, which comprises administering to said mammals an effective amount of a substance having the formula WHEREIN R is selected from the group consisting of OH; NHCH2COOH, and NHCH2CH2SO3H; each X is hydrogen, each Y is hydroxy or acyloxy, and when taken together X and Y is oxo (O ); and the nontoxic pharmaceutically acceptable salts thereof.
Inventors
- 👤 Alan Hugh Weigand
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 13:44
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/56; A61K31/575; C; C07; C07J; C07J41/00; C07J41/0033; C07J41/0055; C07J41/0061; C07J9/00; C07J9/005
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
53 words
THE METHOD OF REDUCING LIPID LEVELS OF HUMAN BEINGS, WHICH COMPRISES; A. ORALLY ADMINISTERING OVER AN EXTENED PERIOD OF TIME, TO A HUMAN BEING IN A HYPERLIPIDEMIC STATE; B. A SMALL BUT EFFECTIVE AMOUNT SUFFICIENT TO EFFECT A REDUCTION OF THE LIPID LEVELS OF SAID HUMAN BEING, OF A COMPOUND OF THE FORMULA:
Claim 2
Independent Claim
53 words
THE METHOD OF REDUCING LIPID LEVELS OF HUMAN BEINGS, WHICH COMPRISES; A. ORALLY ADMINISTERING OVER AN EXTENED PERIOD OF TIME, TO A HUMAN BEING IN A HYPERLIPIDEMIC STATE; B. A SMALL BUT EFFECTIVE AMOUNT SUFFICIENT TO EFFECT A REDUCTION OF THE LIPID LEVELS OF SAID HUMAN BEING, OF A COMPOUND OF THE FORMULA:
Claim 3
Dependent Claim
17 words
The method of claim 1, wherein the compound is 3 Alpha ,7 Alpha -dihydroxy-5 Beta -cholanic acid.
Claim 4
Dependent Claim
21 words
The method of claim 1, wherein the compound is administered in a daily dosage amount of about 750 mg. per day.
Claim 5
Dependent Claim
13 words
The method of claim 1, wherein in the compound each Y is hydroxy.
Claim 6
Dependent Claim
17 words
The method of claim 1, wherein the compound is 3 Alpha ,7 Beta -dihydroxy-5 Beta -cholanic acid.
Claim 7
Independent Claim
54 words
The method of reducing the cholesterol levels of human beings, which comprises; a. orally administering over an extended period of time, to a human being in a hypercholesteremic state; b. a small but effective amount sufficient to effect a reduction in the cholesterol level of said human being, of a compound of the formula:
Claim 8
Independent Claim
54 words
The method of reducing the cholesterol levels of human beings, which comprises; a. orally administering over an extended period of time, to a human being in a hypercholesteremic state; b. a small but effective amount sufficient to effect a reduction in the cholesterol level of said human being, of a compound of the formula:
Claim 9
Dependent Claim
17 words
The method of claim 6, wherein the compound is 3 Alpha ,7 Alpha -dihydroxy-5 Beta -cholanic acid.
Claim 10
Dependent Claim
20 words
The method of claim 6 wherein the compound is administered in a daily dosage amount of 750 mg. per day.
Claim 11
Dependent Claim
15 words
The method of claim 5, wherein the hypercholesteremic state of the human being is hypercholesterolemia.
Claim 12
Dependent Claim
13 words
The method of claim 6, wherein in the compound, each Y is hydroxy.
Claim 13
Dependent Claim
17 words
The method of claim 6, wherein the compound is 3 Alpha ,7 Beta -dihydroxy-5 Beta -cholanic acid.
Claim 14
Independent Claim
54 words
The method of reducing the triglyceride levels of human beings, which comprises; a. orally administering over an extended period of time, to a human being in a hypertriglyceridemic state; b. a small but effective amount sufficient to effect a reduction of the triglyceride level of said human being, of a compound of the formula:
Claim 15
Independent Claim
54 words
The method of reducing the triglyceride levels of human beings, which comprises; a. orally administering over an extended period of time, to a human being in a hypertriglyceridemic state; b. a small but effective amount sufficient to effect a reduction of the triglyceride level of said human being, of a compound of the formula:
Claim 16
Dependent Claim
17 words
The method of claim 12, wherein the compound is 3 Alpha ,7 Alpha -dihydroxy-5 Beta -cholanic acid.
Claim 17
Dependent Claim
21 words
The method of claim 12, wherein the compound is administered in a daily dosage amount of about 750 mg. per day.
Claim 18
Dependent Claim
13 words
The method of claim 12, wherein in the compound, each Y is hydroxy.
Claim 19
Dependent Claim
17 words
The method of claim 12, wherein the compound is 3 Alpha ,7 Beta -dihydroxy-5 Beta -cholanic acid.
Claim 20
Independent Claim
52 words
The method of reducing cholesterol levels of human beings, which comprises; a. Orally administering over an extended period of time, to a human being suffering from cholelithiasis; b. A small but effective amount sufficient to effect a reduction in the cholesterol level of said human being, of a compound of the formula:
Claim 21
Independent Claim
52 words
The method of reducing cholesterol levels of human beings, which comprises; a. Orally administering over an extended period of time, to a human being suffering from cholelithiasis; b. A small but effective amount sufficient to effect a reduction in the cholesterol level of said human being, of a compound of the formula:
Claim 22
Dependent Claim
17 words
The method of claim 17, wherein the compound is 3 Alpha ,7 Alpha -dihydroxy-5 Beta -cholanic acid.
Claim 23
Dependent Claim
17 words
The method of claim 17, wherein the compound is 3 Alpha ,7 Beta -dihydroxy-5 Beta -cholanic acid.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-06 | 1978-07-08 | 1979-01-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-06 | 1982-07-08 | 1983-01-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-06 | 1986-07-08 | 1987-01-07 | $7700.00 | Window Closed / Lapsed |