Patent US3859431A successfully refreshed from Google Patents.
US3859431A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Drug formulations
Assignee: Lilly Industries Ltd
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Filing: 1973-01-04
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Granted: 1975-01-07
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Expires: 1993-01-04
Abstract
Abstract Method for improving the rate of release of physiologically active agents from capsules, and pharmaceutical compositions adapted for filling into capsules, said capsules filled with such compositions having improved rates of release of the physiologically active agent therefrom.
Inventors
- 👤 John Michael Newton
- 👤 Geoffrey Rowley
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:17
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/4841; A61K9/4866; A61J; A61J3/00; A61J3/07; A61J3/071; Y; Y10; Y10S; Y10S206/00; Y10S206/828
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
42 words
A PHARMACEUTICAL TWO-PIECE HARD GELATIN CAPSULE COMPRISING A PHYSIOLOGICALLY ACTIVE AGENT COMMINGLED WITH AN AMOUNT, OF FROM ABOUT 2 TO ABOUT 65 PERCENT BY WEIGHT OF THE PHYSIOLOGICALLY ACTIVE AGENT, AS A RELEASE RATE IMPROVING QUANTITY OF AN ALKALI METAL CARBOXYMETHYL STARCH.
Claim 2
Dependent Claim
42 words
A PHARMACEUTICAL TWO-PIECE HARD GELATIN CAPSULE COMPRISING A PHYSIOLOGICALLY ACTIVE AGENT COMMINGLED WITH AN AMOUNT, OF FROM ABOUT 2 TO ABOUT 65 PERCENT BY WEIGHT OF THE PHYSIOLOGICALLY ACTIVE AGENT, AS A RELEASE RATE IMPROVING QUANTITY OF AN ALKALI METAL CARBOXYMETHYL STARCH.
Claim 3
Dependent Claim
26 words
The pharmaceutical two-piece hard gelatin capsule of claim 1, wherein the alkali metal carboxymethyl starch contains from 15 to 35 carboxymethyl groups per 100 glucose units.
Claim 4
Dependent Claim
15 words
The pharmaceutical two-piece hard gelatin capsule of claim 1, wherein the alkali metal is sodium.
Claim 5
Dependent Claim
38 words
The pharmaceutical two-piece hard gelatin capsule of claim 1, wherein sodium is the alkali metal carboxymethyl starch and is present in an amount of from about 2 to about 65 percent by weight of the physiologically active agent.
Claim 6
Dependent Claim
12 words
The capsule of claim 1, wherein said physiologically active agent is ethinamate.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-06 | 1978-07-08 | 1979-01-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-06 | 1982-07-08 | 1983-01-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-06 | 1986-07-08 | 1987-01-07 | $7700.00 | Window Closed / Lapsed |