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US3854049A Expired / Lapsed US ⏱️ 0.0 years remaining

Compensation for patient thickness variations in differential x-ray transmission imaging

Assignee: Wisconsin Alumni Research Foundation
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Filing: 1973-12-10
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Granted: 1974-12-10
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Expires: 1993-12-10
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Abstract

Abstract Differential x-ray images can be produced by sub-tracting two different x-ray images which are produced by using two different quasi-monoenergetic x-ray spectra. Two different x-ray filters may be employed alternately to produce such spectra. For example, two different filters containing iodine and cerium may be employed alternately to produce two different x-ray spectra having peaks at different energies. The x-rays to be filtered may be derived from an ordinary x-ray tube which produces a continuous spectrum of x-rays over a wide band of energies. The purpose of producing the differential x-ray images is to subtract or cancel out the portions of the x-ray images which are due to the ordinary tissues of the patient, particularly the soft tissues, so that the presence of certain contrast substances in the patient''s body will be emphasized or enhanced. Such contrast substances include iodine, xenon or barium, introduced into the bloodstream, the lungs or the food canal of the patient. The ordinary soft tissues of the patient transmit x-rays of different energies to different extents. While the two different x-ray images can be balanced for any particular thickness of the patient, variations in such thickness over the field of view tend to upset such balance. Thus, without compensation for patient thickness variations, cancellation of the x-ray images due to the ordinary tissues of the patient can be achieved at only one value of patient thickness. In accordance with the present invention, such patient thickness compensation is achieved by adjusting the composition and density of the two x-ray filters, and by adjusting the high voltage supplied to the x-ray tube, so that the ratio of the two different x-ray images produced by soft tissues remains nearly constant over a wide range of patient thickness. Thus, substantial cancellation of the soft tissue images can be achieved over a wide range of variations in the patient thickness. The x-ray filtration is adjusted so that one of the x-ray filters produces a spectrum of transmitted x-rays having two peaks at energies below and above the energy of the peak produced by the other x-ray filter. Thus, the sum of the images produced by the two peaks tends to remain in a constant relationship to the image produced by the other spectrum, despite variations in patient thickness. The supply voltage to the x-ray tube is varied as an inverse function of the average patient thickness. Thus, the voltage is reduced when the average patient thickness increases. The adjustment of the supply voltage to the x-ray tube changes the two different quasi-monoenergetic x-ray spectra so as to optimize the compensation for patient thickness variations.

Inventors

  • 👤 C Mistretta
  • 👤 F Kelcz

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:02
CPC Classifications
A; A61; A61B; A61B6/00; A61B6/50; A61B6/504; A61B6/40; A61B6/4035; A61B6/48; A61B6/482; H; H05; H05G; H05G1/00; H05G1/08; H05G1/60; A61B6/481

Claims Analysis

Total Claims: 33
Claim 1
Independent Claim 105 words
A method of producing differential x-ray images to visualize a contrast material in a patient, comprising the steps of producing a first x-ray image using an x-ray source and first filter, producing a second x-ray image using said x-ray source and a second filter, said filters producing substantially different x-ray spectra, producing a differential image corresponding to the difference between said first and second x-ray images, said contrast material being visualized in said differential image, and adjusting the voltage of said x-ray source as in inverse fuNction of the average patient thickness to minimize the effect of variations in patient thickness upon said differential image.
Claim 2
Independent Claim 105 words
A method of producing differential x-ray images to visualize a contrast material in a patient, comprising the steps of producing a first x-ray image using an x-ray source and first filter, producing a second x-ray image using said x-ray source and a second filter, said filters producing substantially different x-ray spectra, producing a differential image corresponding to the difference between said first and second x-ray images, said contrast material being visualized in said differential image, and adjusting the voltage of said x-ray source as in inverse fuNction of the average patient thickness to minimize the effect of variations in patient thickness upon said differential image.
Claim 3
Dependent Claim 39 words
A method according to claim 1, in which the voltage of said x-ray source is adjusted to a range which produces a flat peak of the ratio between said first and second x-ray images when plotted against patient thickness.
Claim 4
Independent Claim 98 words
A method of producing differential x-ray images, comprising the steps of producing a first x-ray image using a first x-ray spectrum, producing a second x-ray image using a second x-ray spectrum, and producing a differential image corresponding to the difference between said first and second x-ray images, said second spectrum having a spectral element of a predetermined energy, said first x-ray spectrum comprising a low energy spectral element and a high energy spectral element, said low energy spectral element having an energy below said predetermined energy, said high energy spectral element having an energy above said predetermined energy.
Claim 5
Independent Claim 98 words
A method of producing differential x-ray images, comprising the steps of producing a first x-ray image using a first x-ray spectrum, producing a second x-ray image using a second x-ray spectrum, and producing a differential image corresponding to the difference between said first and second x-ray images, said second spectrum having a spectral element of a predetermined energy, said first x-ray spectrum comprising a low energy spectral element and a high energy spectral element, said low energy spectral element having an energy below said predetermined energy, said high energy spectral element having an energy above said predetermined energy.
Claim 6
Dependent Claim 44 words
A method according to claim 3, in which said first and second x-ray spectra are balanced to provide substantially the same image elements in said first and second x-ray images for soft tissue whereby said image elements will cancel out in said differential image.
Claim 7
Dependent Claim 30 words
A method according to claim 4, in which said spectral elements are adjusted to produce substantial balance between said first and second spectra over a substantial range of tissue thickness.
Claim 8
Dependent Claim 28 words
A method according to claim 3, in which said first and second spectra are produced by using first and second x-ray filters in conjunction with an x-ray source.
Claim 9
Dependent Claim 18 words
A method according to claim 6, in which said first and second filters contain iodine and cerium, respectively.
Claim 10
Dependent Claim 56 words
A method according to claim 6, in which said x-ray source includes a high voltage x-ray tube, the supply voltage to said x-ray tube being varied as an inverse function of the average tissue thinkness to maintain a substantial balance between said first and second spectra for soft tissue over a substantial range of tissue thickness.
Claim 11
Dependent Claim 29 words
A method according to claim 6, including the additional step of changing the density of said filters as a direct function of the average tissue thickness of the patient.
Claim 12
Dependent Claim 55 words
A method according to claim 6, including the steps of adjusting the density of said filters as a direct function of the average tissue thickness of the patient while adjusting the x-ray energy of said source as an inverse function of said average tissue thickness to achieve effective compensation for variations in said tissue thickness.
Claim 13
Dependent Claim 37 words
A method according to claim 6, including the steps of adjusting the density of said filters while adjusting the x-ray energy of said source to achieve effective compensation for variations in the tissue thickness of the patient.
Claim 14
Dependent Claim 99 words
A method according to claim 6, including the steps of adjusting the density of said filters while adjusting the x-ray energy of said x-ray source to produce a flat spot in the characteristic curve of TB/TA plotted as a function of patient tissue thickness at a desired average value of patient tissue thickness, where TB is the total of the x-ray photons transmitted through the first filter and the patient while TA is the total of the x-ray photons transmitted through the second filter and the patient, whereby effective compensation is achieved for variations in the patient tissue thickness.
Claim 15
Dependent Claim 18 words
A method according to claim 12, in which said first and second filters contain iodine and cerium, respectively.
Claim 16
Dependent Claim 26 words
A method according to claim 13, in which said filters have iodine and cerium concentrations on the order of 100 to 400 milligrams per square centimeter.
Claim 17
Dependent Claim 22 words
A method according to claim 12, in which said flat spot is in the form of a minimum along said characteristic curve.
Claim 18
Dependent Claim 33 words
A method according to claim 12, iN which said x-ray source includes an x-ray tube supplied with a high voltage, said voltage being adjusted as an inverse function of the patient tissue thickness.
Claim 19
Dependent Claim 18 words
A method according to claim 16, in which said first and second filters contain iodine and cerium, respectively.
Claim 20
Dependent Claim 28 words
A method according to claim 17, in which the iodine and cerium concentrations of the filters are on the order of 100 to 400 milligrams per square centimeter.
Claim 21
Dependent Claim 21 words
A method according to claim 18, in which said high voltage is on the order of 50 to 70 kilovolts peak.
Claim 22
Dependent Claim 21 words
A method according to claim 17, in which said high voltage is on the order of 50 to 70 kilovolts peak.
Claim 23
Dependent Claim 119 words
Apparatus for producing differential x-ray images in which image elements due to the soft tissue of a patient are at least partially cancelled out, comprising x-ray source means for selectively producing first and second x-ray spectra, means for producing first and second x-ray images of the patient using said first and second x-ray spectra, and means for producing a differential image corresponding to the difference between said first and second x-ray images, said second x-ray spectrum having an x-ray spectral element of predetermined energy, said first x-ray spectrum having low and high energy spectral elements, said low energy element having an energy less than said predetermined energy, said high energy element having an energy greater than said predetermined energy.
Claim 24
Dependent Claim 119 words
Apparatus for producing differential x-ray images in which image elements due to the soft tissue of a patient are at least partially cancelled out, comprising x-ray source means for selectively producing first and second x-ray spectra, means for producing first and second x-ray images of the patient using said first and second x-ray spectra, and means for producing a differential image corresponding to the difference between said first and second x-ray images, said second x-ray spectrum having an x-ray spectral element of predetermined energy, said first x-ray spectrum having low and high energy spectral elements, said low energy element having an energy less than said predetermined energy, said high energy element having an energy greater than said predetermined energy.
Claim 25
Dependent Claim 29 words
Apparatus according to claim 21, in which said spectral elements have magnitudes such as to produce substantial balance between said first and second x-ray images for soft patient tissue.
Claim 26
Dependent Claim 36 words
A method according to claim 22, in which said spectral elements are of magnitudes to maintain the balance between said first and second x-ray images for soft tissue over a wide range of tissue thickness variations.
Claim 27
Dependent Claim 31 words
Apparatus according to claim 21, in which said x-ray source means comprises an x-ray source and first and second selectively usable filter means for producing said first and second x-ray spectra.
Claim 28
Dependent Claim 23 words
Apparatus according to claim 24, in which said first and second filter means are movable selectively into operative relation with said x-ray source.
Claim 29
Dependent Claim 18 words
Apparatus according to claim 24, in which said first and second filter means contain iodine and cerium, respectively.
Claim 30
Dependent Claim 31 words
Apparatus according to claim 24, in which said first and second filter means contain iodine and cerium, respectively, in concentrations on the order of 100 to 400 milligrams per square centimeter.
Claim 31
Dependent Claim 35 words
Apparatus according to claim 27, in which said x-ray source includes a high voltage x-ray tube and means for supplying said tube with a high voltage on the order of 50 to 70 kilovolts peak.
Claim 32
Dependent Claim 47 words
An apparatus according to claim 24, in which said first and second filter means contain iodine and cerium, respectively, said x-ray source including a high voltage x-ray tube and means for supplying said tube with a high voltage on the order of 50 to 70 kilovolts peak.
Claim 33
Dependent Claim 27 words
Apparatus according to claim 24, in which said x-ray source comprises a high voltage x-ray tube, and means for varying the high voltage supplied to said tube.

References Cited (Backward Citations)

US3588502A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-12-09 1978-06-10 1978-12-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-12-09 1982-06-10 1982-12-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-12-09 1986-06-10 1986-12-10 $7700.00 Window Closed / Lapsed

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