Patent US3853838A successfully refreshed from Google Patents.
US3853838A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sedative peptides related to acth containing a d-phe moiety
Assignee: Akzona Inc
•
Filing: 1973-07-10
•
Granted: 1974-12-10
•
Expires: 1993-07-10
Abstract
Abstract The invention relates to novel peptides and peptide derivatives of the general formula:
Inventors
- 👤 H Greven
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 15:02
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/10; C07K5/1002; C07K5/1005; C07K5/1013; C07K14/00; C07K14/435; C07K14/665; C07K14/695; C07K14/6955; C07K5/06; C07K5/06104; C07K5/08; C07K5/0802; C07K5/0812; C07K5/1008; C07K5/101; C07K5/1027; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
70 words
A PEPTIDE OF THE FORMULA: A-L-GLU(Q)-L-HISD-X IN WHICH L AND D INDICATE THE CONFIGURATION OF THE RELATIVE RESIDUE AND A IS SELECTED FROM THE GROUP CONSISTING OF H-L-MET, H-L-MET(>O),H-L-MET(>O2), DESAMINOMETHONYL, DESAMINODESAMINO-METHIONYL(>O), DESAMINO-METHIONYL (>O2), AND THE MIETY: H2N-B-CO-, IN WHICH B IS ALKYLENE HAVING 1-6 CARBON ATOMS, Q IS SELECTED FROM THE GROUP CONSISTING OF HYDROXY AND AMINO, X IS SELECTED FROM A (N-PHENYL BRANCHED ALKYL) AMINO GROUP OF THE FORMULA
Claim 2
Dependent Claim
70 words
A PEPTIDE OF THE FORMULA: A-L-GLU(Q)-L-HISD-X IN WHICH L AND D INDICATE THE CONFIGURATION OF THE RELATIVE RESIDUE AND A IS SELECTED FROM THE GROUP CONSISTING OF H-L-MET, H-L-MET(>O),H-L-MET(>O2), DESAMINOMETHONYL, DESAMINODESAMINO-METHIONYL(>O), DESAMINO-METHIONYL (>O2), AND THE MIETY: H2N-B-CO-, IN WHICH B IS ALKYLENE HAVING 1-6 CARBON ATOMS, Q IS SELECTED FROM THE GROUP CONSISTING OF HYDROXY AND AMINO, X IS SELECTED FROM A (N-PHENYL BRANCHED ALKYL) AMINO GROUP OF THE FORMULA
Claim 3
Dependent Claim
23 words
A peptide according to claim 1 of the formula: A-L-Glu(Q)-L-His-D-Phe-Y in which A, Q and Y have the meanings indicated in claim 1.
Claim 4
Dependent Claim
31 words
A peptide according to claim 1 of the formula: A-L-Glu(Q)-L-His-D-Phe-T-Z, in which A, Q and Z have the meanings indicated in claim 1, and T is selected from L-Lys and L-Arg.
Claim 5
Dependent Claim
30 words
A peptide according to claim 1 of the formula: A-L-Glu(Q)-L-His-D-Phe-T-Phe-OH, in which A and Q have the meanings indicated in claim 1 and T is selected from L-Arg and L-Lys.
Claim 6
Dependent Claim
30 words
A peptide according to claim 1 of the formula: A-L-Glu(Q)-L-His-D-Phe-T-Indolylethylamino in which A and Q have the meanings indicated in claim 1 and T is selected from L-Arg and L-Lys.
Claim 7
Dependent Claim
25 words
A peptide according to claim 1 in which A is selected from the group consisting of Met, desamino-methionyl and the corresponding sulfoxides and sulfones thereof.
Claim 8
Dependent Claim
14 words
A metal complex of the peptides and peptide derivatives as claimed in claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-12-09 | 1978-06-10 | 1978-12-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-12-09 | 1982-06-10 | 1982-12-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-12-09 | 1986-06-10 | 1986-12-10 | $7700.00 | Window Closed / Lapsed |